Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2826091 | 0.81 | NPSR1 (1.00) | MAPTNPSR1GAASMN1; SMN2LMNA | |
| SCHEMBL28879006 | 0.81 | MAPT (0.68) | MAPTNPSR1GAASMN1; SMN2LMNA | |
| SCHEMBL28878936 | 0.81 | GAA (0.63) | MAPTNPSR1GAASMN1; SMN2LMNA | |
| SCHEMBL3776440 | 0.78 | LMNA (0.69) | MAPTNPSR1GAASMN1; SMN2LMNA | |
| SCHEMBL8776502 | 0.74 | HTT (0.61) | MAPTNPSR1GAASMN1; SMN2LMNA | |
| SCHEMBL27618204 | 0.74 | NPSR1 (0.58) | MAPTNPSR1GAASMN1; SMN2LMNA | |
| SCHEMBL11381046 | 0.72 | LMNA (0.61) | MAPTNPSR1GAASMN1; SMN2LMNA | |
| SCHEMBL2820932 | 0.72 | ALDH1A1 (0.82) | MAPTNPSR1GAASMN1; SMN2HTT | |
| SCHEMBL3775455 | 0.72 | LMNA (0.49) | MAPTNPSR1GAASMN1; SMN2LMNA | |
| SCHEMBL3788035 | 0.72 | ALDH1A1 (0.51) | MAPTNPSR1GAASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114249689-A | Synthetic method of benzoyl quinoline compound | 温州大学 | 2022-03-29 | — | — | CN | disclosed |