Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ACLY | P53396 | 1/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8610261 | 0.85 | PTGS2 (0.58) | — | |
| SCHEMBL12345585 | 0.85 | ALDH1A1 (0.54) | APPTSHRCYP2C9HTTNPC1 | |
| SCHEMBL12345589 | 0.85 | HTT (0.59) | APPTSHRCYP2C9HTTNPC1 | |
| SCHEMBL12091653 | 0.84 | KDM4E (0.61) | APPTSHRNPC1HAO1KMT2A | |
| SCHEMBL5605369 | 0.83 | APP (0.64) | APPTSHRCYP2C9HTTNPC1 | |
| SCHEMBL13707395 | 0.83 | APP (0.56) | APPTSHRCYP2C9HTTNPC1 | |
| SCHEMBL15353458 | 0.83 | CYP2C9 (0.40) | APPTSHRCYP2C9HTTKMT2A | |
| SCHEMBL12345600 | 0.82 | TSHR (0.50) | APPTSHRCYP2C9HTTNPC1 | |
| SCHEMBL12979949 | 0.82 | HTT (0.56) | APPTSHRCYP2C9HTTNPC1 | |
| SCHEMBL12980914 | 0.82 | HTT (0.56) | APPTSHRCYP2C9HTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109400518-B | Polysubstituted 6-arylbenzo [ a ] carbazole derivative and synthetic method thereof | 湘潭大学 | 2021-09-24 | — | — | CN | claimed |
| CN-108997329-B | Polysubstituted 3- (3-benzo [ b ] selenophenyl) -1H-2-aryl indole and derivative and synthesis method thereof | 湘潭大学 | 2021-06-04 | — | — | CN | claimed |
| CN-109400518-A | Polysubstituted 6- aryl benzo [a] carbazole and derivative and its synthetic method | 湘潭大学 | 2019-03-01 | — | — | CN | claimed |
| CN-109400518-B | Polysubstituted 6-arylbenzo [ a ] carbazole derivative and synthetic method thereof | 湘潭大学 | 2021-09-24 | — | — | CN | disclosed |
| CN-108997329-B | Polysubstituted 3- (3-benzo [ b ] selenophenyl) -1H-2-aryl indole and derivative and synthesis method thereof | 湘潭大学 | 2021-06-04 | — | — | CN | disclosed |
| CN-109400518-A | Polysubstituted 6- aryl benzo [a] carbazole and derivative and its synthetic method | 湘潭大学 | 2019-03-01 | — | — | CN | disclosed |
| CN-108997329-A | Polysubstituted 3-(3- benzo [b] selenophen base) -1H-2- (hetero) aryl indole and derivative and its synthetic method | 湘潭大学 | 2018-12-14 | — | — | CN | disclosed |