Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 1.00 |
| ▸ | MAPT | P10636 | 7/20 | 1.00 |
| ▸ | HPGD | P15428 | 7/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 1.00 |
| ▸ | TSHR | P16473 | 4/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.70 |
| ▸ | HTT | P42858 | 1/20 | 0.70 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.70 |
| ▸ | TP53 | P04637 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 4/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7861772 | 0.79 | MAPT (0.66) | KDM4EMAPTHPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL6277710 | 0.77 | KDM4E (0.81) | KDM4EMAPTHPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL9675696 | 0.76 | TSHR (0.61) | KDM4EMAPTHPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL982188 | 0.74 | KDM4E (1.00) | KDM4EMAPTHPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL14601420 | 0.73 | KDM4E (0.57) | KDM4EMAPTHPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL1544047 | 0.72 | KDM4E (0.56) | KDM4EMAPTHPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL8010723 | 0.72 | ESR2 (0.79) | KDM4EMAPTHPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL7725095 | 0.71 | KDM4E (1.00) | KDM4EMAPTHPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL2607499 | 0.70 | KDM4E (0.64) | KDM4EMAPTHPGDHSD17B10TSHR | |
| SCHEMBL2607509 | 0.69 | KDM4E (0.66) | KDM4EMAPTHPGDALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108997221-B | Method for synthesizing 1, 2-disubstituted benzimidazole compound by using 3-hydroxy-2-naphthoic acid and dichlorotitanocene | 陕西师范大学 | 2021-10-01 | — | — | CN | disclosed |
| CN-108997221-A | The method that 3- hydroxy-2-naphthoic acid cooperates with cyclopentadienyl titanium dichloride synthesis 1,2- disubstituted benzenes and glyoxaline compound | 陕西师范大学 | 2018-12-14 | — | — | CN | disclosed |