Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.61 |
| ▸ | HPGD | P15428 | 6/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | VDR | P11473 | 2/20 | 0.56 |
| ▸ | CFTR | P13569 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7861772 | 0.78 | MAPT (0.66) | TSHRKDM4EHPGDMAPTHSD17B10 | |
| SCHEMBL2084701 | 0.78 | VDR (0.72) | KDM4EHPGDMAPTSMN1; SMN2VDR | |
| SCHEMBL28261636 | 0.76 | KDM4E (1.00) | TSHRKDM4EHPGDMAPTHSD17B10 | |
| SCHEMBL376921 | 0.74 | VDR (0.71) | TSHRKDM4EHPGDMAPTVDR | |
| SCHEMBL9674712 | 0.74 | VDR (0.58) | KDM4EHPGDMAPTHSD17B10SMN1; SMN2 | |
| SCHEMBL3616241 | 0.74 | KDM4E (0.65) | KDM4EHPGDMAPTHSD17B10SMN1; SMN2 | |
| SCHEMBL28425872 | 0.73 | RAB9A (0.67) | TSHRKDM4EHPGDMAPTSMN1; SMN2 | |
| SCHEMBL29870926 | 0.73 | RAB9A (0.67) | TSHRKDM4EHPGDMAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4727347 | 0.72 | VDR (0.56) | KDM4EHPGDMAPTHSD17B10SMN1; SMN2 | |
| SCHEMBL9866483 | 0.72 | ALDH1A1 (0.67) | TSHRKDM4EHPGDMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0276942-B1 | 6-BETA(SUBSTITUTED)-(S)-HYDROXYMETHYLPENICILLANIC ACIDS AND DERIVATIVES THEREOF | PFIZER INC. (US) | 1992-04-01 | — | — | EP | disclosed |
| US-4782050-A | BACTERICIDES | PFIZER INC. (US) | 1988-11-01 | — | — | US | disclosed |
| EP-0276942-A1 | 6-Beta(substituted)-(S)-hydroxymethylpenicillanic acids and derivatives thereof | PFIZER INC. (US) | 1988-08-03 | — | — | EP | disclosed |