Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.53 |
| ▸ | HCAR3 | P49019 | 4/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | RARA | P10276 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5572514 | 0.98 | RARB (0.55) | RARBHCAR3NFKB1NPC1RAB9A | |
| SCHEMBL27716846 | 0.94 | HCAR3 (0.49) | RARBHCAR3NFKB1NPC1RAB9A | |
| SCHEMBL7092189 | 0.84 | EPHX2 (0.44) | RARBHCAR3NFKB1NPC1RAB9A | |
| SCHEMBL9733700 | 0.82 | RARB (0.66) | RARBNFKB1NPC1RAB9ANFKB2 | |
| SCHEMBL28511100 | 0.81 | RARB (0.39) | RARBHCAR3NFKB1NPC1RAB9A | |
| SCHEMBL186656 | 0.78 | ALDH1A1 (0.52) | HCAR3NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL10663476 | 0.77 | HCAR3 (0.57) | RARBHCAR3NFKB1NPC1RAB9A | |
| SCHEMBL11610777 | 0.77 | RARB (0.76) | RARBNFKB1NPC1RAB9ANFKB2 | |
| SCHEMBL10658847 | 0.76 | RARB (0.58) | RARBHCAR3NFKB1NPC1RAB9A | |
| SCHEMBL10666643 | 0.76 | RARB (0.58) | RARBHCAR3NFKB1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108884058-A | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | 阿奇克斯制药公司 | 2018-11-23 | — | — | CN | disclosed |