Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | PREP | P48147 | 1/20 | 0.35 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28263140 | 0.90 | KAT6A (0.39) | CCR5HDAC4KMT2APREPL3MBTL1 | |
| SCHEMBL28263101 | 0.87 | HDAC4 (0.40) | HDAC4KMT2AL3MBTL1ALDH1A1LMNA | |
| SCHEMBL28263120 | 0.84 | CDC25B (0.37) | KMT2APOLBLMNAMEN1MAPT | |
| SCHEMBL28261964 | 0.84 | KMT2A (0.35) | KMT2AL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL28263128 | 0.83 | KMT2A (0.42) | HDAC4ELANEHCRTR1HCRTR2KMT2A | |
| SCHEMBL28263118 | 0.82 | HSD11B1 (0.41) | KMT2AALDH1A1MEN1MAPTKDM4E | |
| SCHEMBL28263098 | 0.82 | KMT2A (0.36) | HDAC4KMT2AMEN1MAPTKDM4E | |
| SCHEMBL28867359 | 0.81 | HTT (0.38) | KMT2AL3MBTL1ALDH1A1MEN1NPSR1 | |
| SCHEMBL28261985 | 0.81 | RORC (0.45) | KMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL28261953 | 0.79 | KMT2A (0.36) | HDAC4HCRTR2KMT2AMEN1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071457-A | Inhibitors of indoleamine 2, 3-dioxygenase | 荷兰转化研究中心有限责任公司 | 2018-12-21 | — | — | CN | disclosed |