Dimethylamine

Dimethylamine

SCHEMBL28262136

CNC.O=C(O)COc1ccc(Cl)cc1

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.61
TDP1 Q9NUW8 1/20 0.61
ALOX15 P16050 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.56
MCL1 Q07820 1/20 0.56
PTGS2 P35354 1/20 0.55
ALDH1A1 P00352 3/20 0.54
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
MAPT P10636 2/20 0.54
PTPN7 P35236 1/20 0.54
PTPN12 Q05209 1/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
ATF4 P18848 3/20 0.53
KDM4E B2RXH2 1/20 0.53
LMNA P02545 1/20 0.53
MAP4K4 O95819 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL40485 0.92 ALOX15 (0.65) TDP1ALOX15SMN1; SMN2MCL1ALDH1A1
SCHEMBL30969690 0.92 ALOX15 (0.65) TDP1ALOX15SMN1; SMN2MCL1ALDH1A1
Acetic Acid SCHEMBL10534942 0.91 ALOX15 (0.59) TSHRTDP1ALOX15SMN1; SMN2MCL1
SCHEMBL29240036 0.90 ALOX15 (0.63) TDP1ALOX15SMN1; SMN2MCL1ALDH1A1
Hydrochloric Acid SCHEMBL11104858 0.90 ALOX15 (0.63) TDP1ALOX15SMN1; SMN2MCL1ALDH1A1
SCHEMBL27313420 0.90 ALOX15 (0.63) TDP1ALOX15SMN1; SMN2MCL1ALDH1A1
Ammonia Solution, Strong SCHEMBL28895431 0.90 ALOX15 (0.63) TDP1ALOX15SMN1; SMN2MCL1ALDH1A1
SCHEMBL31134770 0.90 ALDH1A1 (0.63) TDP1ALOX15SMN1; SMN2MCL1ALDH1A1
SCHEMBL27364334 0.90 ALOX15 (0.63) TDP1ALOX15SMN1; SMN2MCL1ALDH1A1
Hydrochloric Acid SCHEMBL5903375 0.90 ALOX15 (0.63) TDP1ALOX15SMN1; SMN2MCL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108947807-A A kind of preparation method of chlorobenzene oxycarboxylic acid amine salt 山东润博生物科技有限公司 2018-12-07 CN disclosed
CN-108947806-A A kind of preparation method of chlorobenzene oxycarboxylic acid amine salt 山东润博生物科技有限公司 2018-12-07 CN disclosed