Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.47 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.47 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4599396 | 0.82 | TP53 (0.69) | KMT2ATSHRMAPTALDH1A1MEN1 | |
| SCHEMBL4598556 | 0.79 | MAPT (0.62) | KMT2ATSHRMAPTALDH1A1MEN1 | |
| SCHEMBL28263497 | 0.78 | GAA (0.53) | KMT2AMAPTALDH1A1MEN1L3MBTL1 | |
| SCHEMBL28360244 | 0.78 | MEN1 (0.53) | KMT2ATSHRMAPTALDH1A1MEN1 | |
| SCHEMBL4312525 | 0.77 | MAPT (0.54) | KMT2ATSHRMAPTALDH1A1MEN1 | |
| SCHEMBL27570585 | 0.77 | KMT2A (0.54) | KMT2ATSHRMAPTALDH1A1MEN1 | |
| SCHEMBL30606801 | 0.75 | MAPT (0.87) | KMT2AMAPTALDH1A1MEN1L3MBTL1 | |
| SCHEMBL29580531 | 0.75 | MAPT (0.87) | KMT2AMAPTALDH1A1MEN1L3MBTL1 | |
| SCHEMBL5554181 | 0.75 | MAPT (0.57) | KMT2AMAPTALDH1A1MEN1TP53 | |
| SCHEMBL24755632 | 0.74 | CYP1A2 (0.61) | KMT2ATSHRMAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108929324-A | The preparation and application of novel 1,1- cyclopropyl diamide derivatives | 南开大学 | 2018-12-04 | — | — | CN | disclosed |