Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 6/20 | 0.52 |
| ▸ | NPC1 | O15118 | 6/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28263497 | 0.82 | GAA (0.53) | MEN1KMT2ARAB9ANPC1GAA | |
| SCHEMBL5554181 | 0.81 | MAPT (0.57) | MEN1KMT2ARAB9AGAASMN1; SMN2 | |
| SCHEMBL306352 | 0.81 | KMT2A (0.53) | MEN1KMT2ARAB9ANPC1GAA | |
| SCHEMBL27923186 | 0.81 | GAA (0.62) | MEN1KMT2ARAB9ANPC1GAA | |
| SCHEMBL4312525 | 0.80 | MAPT (0.54) | MEN1KMT2ARAB9ANPC1GAA | |
| SCHEMBL28262349 | 0.78 | KMT2A (0.55) | MEN1KMT2AGAASMN1; SMN2TSHR | |
| SCHEMBL7864456 | 0.77 | GAA (0.47) | GAAALDH1A1 | |
| SCHEMBL2091913 | 0.77 | MEN1 (0.62) | MEN1KMT2ARAB9ANPC1GAA | |
| SCHEMBL15000050 | 0.77 | MEN1 (0.54) | MEN1KMT2ARAB9ANPC1GAA | |
| SCHEMBL28863079 | 0.77 | RAB9A (0.50) | KMT2ARAB9ANPC1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106349158-B | C-Met small molecule inhibitor, pharmaceutical composition containing same and pharmaceutical application thereof | 杭州市西溪医院 | 2020-02-28 | — | — | CN | disclosed |