Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14746960 | 0.88 | RAB9A (0.48) | RAB9ANPC1SMN1; SMN2NPSR1KMT2A | |
| SCHEMBL28160421 | 0.82 | GAA (0.53) | RAB9ANPC1KMT2AMEN1ALDH1A1 | |
| SCHEMBL4744831 | 0.80 | SMN1; SMN2 (0.67) | RAB9ANPC1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL19605723 | 0.76 | RAB9A (0.50) | RAB9ANPC1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL4312525 | 0.76 | MAPT (0.54) | RAB9ANPC1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL513736 | 0.75 | RAB9A (0.64) | RAB9ANPC1SMN1; SMN2NPSR1KMT2A | |
| SCHEMBL21059184 | 0.75 | NPC1 (0.58) | RAB9ANPC1SMN1; SMN2NPSR1KMT2A | |
| SCHEMBL513735 | 0.74 | RAB9A (0.62) | RAB9ANPC1SMN1; SMN2NPSR1KMT2A | |
| SCHEMBL43074 | 0.73 | HDAC3 (0.69) | RAB9ANPC1SMN1; SMN2NPSR1KMT2A | |
| SCHEMBL306352 | 0.73 | KMT2A (0.53) | RAB9ANPC1SMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108929324-A | The preparation and application of novel 1,1- cyclopropyl diamide derivatives | 南开大学 | 2018-12-04 | — | — | CN | disclosed |
| CN-108503650-A | Dioxane and quinazoline compounds or its pharmaceutical salts or its hydrate and its application as tyrosine kinase inhibitor | 北京赛特明强医药科技有限公司 | 2018-09-07 | — | — | CN | disclosed |