Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 7/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 5/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.39 |
| ▸ | USP10 | Q14694 | 1/20 | 0.39 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.39 |
| ▸ | USP13 | Q92995 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17410801 | 0.81 | EGFR (0.60) | EGFRALOX5PIK3CAPIK3CD | |
| SCHEMBL29891394 | 0.81 | EGFR (0.60) | EGFRALOX5PIK3CAPIK3CD | |
| SCHEMBL28178783 | 0.78 | PIK3CA (0.61) | EGFRPIK3CAPIK3CDUSP2CYP1A2 | |
| SCHEMBL28292983 | 0.77 | CYP2D6 (0.47) | EGFRPIK3CAPIK3CDUSP2CYP1A2 | |
| SCHEMBL2573576 | 0.76 | EGFR (0.59) | EGFRALOX5PIK3CAPIK3CDMET | |
| SCHEMBL6998128 | 0.76 | EGFR (0.55) | EGFRALOX5PIK3CAPIK3CDMET | |
| SCHEMBL30918007 | 0.76 | EGFR (0.55) | EGFRALOX5PIK3CAPIK3CDCYP1A2 | |
| SCHEMBL22315252 | 0.76 | EGFR (0.55) | EGFRALOX5PIK3CAPIK3CDMET | |
| SCHEMBL9253314 | 0.76 | EGFR (0.55) | EGFRALOX5PIK3CAPIK3CDMET | |
| SCHEMBL3821058 | 0.76 | EGFR (0.55) | EGFRALOX5PIK3CAPIK3CDMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103623033-B | Euphorbiaceae plant active substance for inhibiting cancer and/or tumor cell growth and application thereof | 福又达生物科技股份有限公司 | 2018-12-21 | — | — | CN | claimed |