Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | XDH | P47989 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29721687 | 0.89 | CA1 (0.50) | CA1CA2ALDH1A1CA12CA7 | |
| SCHEMBL288320 | 0.81 | MAPT (0.54) | CA1CA2ALDH1A1CA12CA7 | |
| SCHEMBL30445913 | 0.81 | MAPT (0.54) | CA1CA2ALDH1A1CA12CA7 | |
| SCHEMBL2898350 | 0.81 | ALDH1A1 (0.47) | CA1CA2ALDH1A1CA12CA7 | |
| SCHEMBL29906783 | 0.81 | ALDH1A1 (0.47) | CA1CA2ALDH1A1CA12CA7 | |
| Hydrochloric Acid SCHEMBL699425 | 0.80 | MAPT (0.53) | CA1CA2ALDH1A1CA12CA7 | |
| Hydrochloric Acid SCHEMBL3102567 | 0.80 | ALDH1A1 (0.46) | CA1CA2ALDH1A1CA12CA7 | |
| Hydrochloric Acid SCHEMBL29940234 | 0.80 | ALDH1A1 (0.46) | CA1CA2ALDH1A1CA12CA7 | |
| SCHEMBL45146 | 0.79 | MAPT (0.68) | CA1CA2ALDH1A1CA12CA7 | |
| SCHEMBL22226391 | 0.79 | ALDH1A1 (0.51) | CA1CA2ALDH1A1CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108997229-B | 1,2,3, 4-tetrahydroquinoxaline-6-carboxylic acid methyl ester and preparation method thereof | 郑州轻工业学院 | 2020-05-05 | — | — | CN | claimed |
| CN-108997229-A | 1,2,3,4- tetrahydroquinoxaline -6- carboxylate methyl ester and preparation method thereof | 郑州轻工业学院 | 2018-12-14 | — | — | CN | claimed |
| CN-108997229-B | 1,2,3, 4-tetrahydroquinoxaline-6-carboxylic acid methyl ester and preparation method thereof | 郑州轻工业学院 | 2020-05-05 | — | — | CN | disclosed |
| CN-108997229-B | 1,2,3, 4-tetrahydroquinoxaline-6-carboxylic acid methyl ester and preparation method thereof | 郑州轻工业学院 | 2020-05-05 | — | — | CN | disclosed |
| CN-108997229-B | 1,2,3, 4-tetrahydroquinoxaline-6-carboxylic acid methyl ester and preparation method thereof | 郑州轻工业学院 | 2020-05-05 | — | — | CN | disclosed |
| CN-110573154-A | Compositions and methods for modulating short-chain dehydrogenase activity | 卡斯西部储备大学 | 2019-12-13 | — | — | CN | disclosed |
| CN-108997229-A | 1,2,3,4- tetrahydroquinoxaline -6- carboxylate methyl ester and preparation method thereof | 郑州轻工业学院 | 2018-12-14 | — | — | CN | disclosed |
| CN-108997229-A | 1,2,3,4- tetrahydroquinoxaline -6- carboxylate methyl ester and preparation method thereof | 郑州轻工业学院 | 2018-12-14 | — | — | CN | disclosed |
| CN-108997229-A | 1,2,3,4- tetrahydroquinoxaline -6- carboxylate methyl ester and preparation method thereof | 郑州轻工业学院 | 2018-12-14 | — | — | CN | disclosed |