Benzene

Benzene

SCHEMBL28264641

CC=C(C=O)c1ccccc1.c1ccccc1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.52
TDP1 Q9NUW8 2/20 0.52
MAPK1 P28482 1/20 0.52
TSHR P16473 5/20 0.44
LMNA P02545 2/20 0.42
F2 P00734 1/20 0.42
CES2 O00748 4/20 0.42
CES1 P23141 4/20 0.42
DAO P14920 1/20 0.42
NAPRT Q6XQN6 1/20 0.42
TP53 P04637 1/20 0.40
AKT1 P31749 1/20 0.39
POLB P06746 2/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
CYP3A4 P08684 1/20 0.39
PARP1 P09874 1/20 0.39
MAPT P10636 1/20 0.39
CYP2C19 P33261 1/20 0.39
RECQL P46063 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL950633 1.00 ALDH1A1 (0.52) ALDH1A1TDP1MAPK1TSHRLMNA
SCHEMBL262669 1.00 ALDH1A1 (0.52) ALDH1A1TDP1MAPK1TSHRLMNA
SCHEMBL19792666 1.00 ALDH1A1 (0.52) ALDH1A1TDP1MAPK1TSHRLMNA
SCHEMBL27671955 0.82 PARP10 (0.52) ALDH1A1TSHRPOLBMAPT
SCHEMBL9865404 0.81 TSHR (0.55) ALDH1A1TDP1TSHRCES2CES1
SCHEMBL18946033 0.81 ALDH1A1 (0.43) ALDH1A1TDP1MAPK1TSHRCES2
SCHEMBL3722947 0.80 ALDH1A1 (0.52) ALDH1A1TDP1MAPK1TSHRLMNA
SCHEMBL3722948 0.80 ALDH1A1 (0.52) ALDH1A1TDP1MAPK1TSHRLMNA
SCHEMBL6786358 0.78 NQO2 (0.57) ALDH1A1TDP1MAPK1TSHRLMNA
SCHEMBL11156464 0.78 ALDH1A1 (0.50) ALDH1A1TDP1MAPK1TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109068671-A Flavor milk product 雀巢产品技术援助有限公司 2018-12-21 CN disclosed