Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL27431148 | 0.83 | TSHR (0.71) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 | |
| SCHEMBL19792666 | 0.81 | ALDH1A1 (0.52) | TSHRTP53ALDH1A1KMT2ACA1 | |
| Benzene SCHEMBL28264641 | 0.81 | ALDH1A1 (0.52) | TSHRTP53ALDH1A1KMT2ACA1 | |
| SCHEMBL950633 | 0.81 | ALDH1A1 (0.52) | TSHRTP53ALDH1A1KMT2ACA1 | |
| SCHEMBL262669 | 0.81 | ALDH1A1 (0.52) | TSHRTP53ALDH1A1KMT2ACA1 | |
| SCHEMBL26393544 | 0.80 | TSHR (0.52) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 | |
| SCHEMBL11083064 | 0.79 | POLB (0.51) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 | |
| SCHEMBL11083067 | 0.79 | POLB (0.51) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 | |
| SCHEMBL6786351 | 0.79 | NQO2 (0.57) | TSHRTP53ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL6786358 | 0.79 | NQO2 (0.57) | TSHRTP53ALDH1A1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011938-A | Antimicrobials | ELI LILLY AND COMPANY (US) | 1991-04-30 | — | — | US | disclosed |
| US-4940718-A | BACTERICIDES | ELI LILLY AND COMPANY (US) | 1990-07-10 | — | — | US | disclosed |
| EP-0202046-A1 | 7-Substituted bicyclic pyrazolidinones | ELI LILLY AND COMPANY (US) | 1986-11-20 | — | — | EP | disclosed |