Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.50 |
| ▸ | KDR | P35968 | 3/20 | 0.49 |
| ▸ | FLT1 | P17948 | 2/20 | 0.49 |
| ▸ | FLT4 | P35916 | 2/20 | 0.49 |
| ▸ | COMT | P21964 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.47 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12077033 | 0.91 | KDR (0.55) | MAPTNPSR1TSHRRAB9ALMNA | |
| SCHEMBL28600687 | 0.89 | KMT2A (0.46) | MAPTNPSR1TSHRRAB9ALMNA | |
| SCHEMBL11385870 | 0.87 | KDR (0.58) | MAPTTSHRRAB9ALMNAKDR | |
| SCHEMBL11771718 | 0.85 | KDR (0.49) | RAB9ADYRK1ACLK4KDRTP53 | |
| SCHEMBL23382222 | 0.84 | KDR (0.59) | MAPTLMNADYRK1ACLK4KDR | |
| SCHEMBL30878105 | 0.84 | KDR (0.59) | MAPTLMNADYRK1ACLK4KDR | |
| SCHEMBL15315965 | 0.83 | TUBB4A (0.44) | MAPTRAB9ALMNADYRK1ACLK4 | |
| SCHEMBL28186197 | 0.81 | KDR (0.55) | RAB9ACLK4KDRFLT1FLT4 | |
| SCHEMBL3278138 | 0.81 | MAPK9 (0.58) | RAB9ADYRK1AKDRTP53MAPK9 | |
| SCHEMBL12076906 | 0.81 | KDR (0.50) | MAPTNPSR1TSHRRAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109096139-B | Preparation method of alpha-carbonyl amide derivative | 贵州大学 | 2021-03-02 | — | — | CN | disclosed |
| CN-109096139-A | A kind of preparation method of alpha-carbonyl amide derivatives | 贵州大学 | 2018-12-28 | — | — | CN | disclosed |