SCHEMBL28264992

SCHEMBL28264992

COc1ccc(CCC(O)c2cc(C)ccc2O)c(OC)c1

nearest known ligand 0.73

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
ADRA2A P08913 1/20 0.42
ADRA1A P35348 1/20 0.42
APLNR P35414 1/20 0.41
BCHE P06276 1/20 0.40
TYR P14679 1/20 0.40
ACHE P22303 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2967799 0.92 ADRA2A (0.49) MEN1KMT2AADRA2AADRA1AAPLNR
SCHEMBL29684654 0.92 ADRA2A (0.49) MEN1KMT2AADRA2AADRA1AAPLNR
SCHEMBL2965867 0.84 BCHE (0.49) MEN1KMT2AADRA2AADRA1AAPLNR
SCHEMBL29684861 0.84 BCHE (0.49) MEN1KMT2AADRA2AADRA1AAPLNR
SCHEMBL2976761 0.74 STAT3 (0.56) ADRA2AADRA1A
SCHEMBL15218636 0.70 POLB (0.43) MEN1KMT2AAPLNR
SCHEMBL6291795 0.70 ALDH1A1 (0.46) MEN1KMT2AAPLNR
SCHEMBL29290893 0.69 ESR1 (0.69) APLNRTYR
SCHEMBL266620 0.69 HTR2A (0.57) MEN1KMT2AADRA1AAPLNR
SCHEMBL27911912 0.69 POLB (0.54) TYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109134205-A Diaryl alkane as binuclear enzymes potent inhibitor 尤尼根公司 2019-01-04 CN disclosed