SCHEMBL28265201

SCHEMBL28265201

C=CC(=O)OCC(CO)CCC(CC)CO

nearest known ligand 0.66

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.66
ALDH1A1 P00352 6/20 0.42
CYP3A4 P08684 4/20 0.42
TP53 P04637 3/20 0.42
HIF1A Q16665 3/20 0.42
MAPK1 P28482 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
HPGD P15428 1/20 0.42
HSD17B10 Q99714 1/20 0.37
TDP1 Q9NUW8 2/20 0.37
ATM Q13315 1/20 0.37
THRB P10828 1/20 0.36
CA2 P00918 1/20 0.33
RECQL P46063 1/20 0.31
PRSS1 P07477 1/20 0.31
PRSS2 P07478 1/20 0.31
PRSS3 P35030 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL869655 0.91 TSHR (0.67) TSHRALDH1A1CYP3A4TP53HIF1A
SCHEMBL5188758 0.87 TSHR (0.88) TSHRALDH1A1CYP3A4MAPK1HPGD
SCHEMBL21409688 0.86 TSHR (0.61) TSHRALDH1A1CYP3A4TP53HIF1A
SCHEMBL74390 0.85 TSHR (0.73) TSHRALDH1A1CYP3A4TP53HIF1A
SCHEMBL5027331 0.85 TSHR (0.79) TSHRALDH1A1CYP3A4TP53HIF1A
SCHEMBL19845060 0.84 TSHR (0.54) TSHRALDH1A1CYP3A4TP53HIF1A
SCHEMBL11545972 0.84 TSHR (0.73) TSHRALDH1A1CYP3A4TP53HIF1A
Benzene SCHEMBL11786070 0.84 TSHR (0.81) TSHRALDH1A1CYP3A4MAPK1HPGD
SCHEMBL6230188 0.83 TSHR (0.59) TSHRALDH1A1CYP3A4TP53HIF1A
SCHEMBL14463069 0.83 TSHR (0.59) TSHRALDH1A1CYP3A4TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110387138-A Methylidyne compound, colored resin composition, coloring cured film and its manufacturing method, colored filter, printing ink and application thereof 日本化药株式会社 2019-10-29 CN disclosed
CN-105384728-B Epoxy carboxylic acids' ester compounds and hardening thing containing its resin combination and the resin combination 日本化药株式会社 2018-12-21 CN disclosed