Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.81 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | KDM4C | Q9H3R0 | 9/20 | 0.50 |
| ▸ | KDM4D | Q6B0I6 | 5/20 | 0.50 |
| ▸ | KDM6B | O15054 | 5/20 | 0.45 |
| ▸ | KDM5A | P29375 | 2/20 | 0.44 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 4/20 | 0.42 |
| ▸ | CNR1 | P21554 | 3/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28589808 | 0.90 | SLC22A12 (1.00) | SLC22A12KDM4ECNR2CNR1LMNA | |
| SCHEMBL28589203 | 0.89 | SLC22A12 (0.65) | SLC22A12KDM4ECNR2CNR1LMNA | |
| SCHEMBL28577788 | 0.85 | SLC22A12 (0.79) | SLC22A12KDM4EKDM4CKDM4DCNR2 | |
| SCHEMBL29929026 | 0.85 | SLC22A12 (0.79) | SLC22A12KDM4EKDM4CKDM4DCNR2 | |
| SCHEMBL28914750 | 0.84 | SLC22A12 (0.78) | SLC22A12KDM4ECNR2CNR1LMNA | |
| SCHEMBL28583458 | 0.84 | SLC22A12 (0.78) | SLC22A12KDM4ECNR2CNR1LMNA | |
| SCHEMBL28573465 | 0.83 | SLC22A12 (0.76) | SLC22A12KDM4ECNR2CNR1LMNA | |
| SCHEMBL28265757 | 0.82 | SLC22A12 (0.74) | SLC22A12KDM4ECNR2CNR1LMNA | |
| SCHEMBL28914786 | 0.82 | SLC22A12 (0.78) | SLC22A12KDM4ECNR2CNR1LMNA | |
| SCHEMBL30089337 | 0.82 | SLC22A12 (0.78) | SLC22A12KDM4ECNR2CNR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113004188-B | Indole derivative, preparation method and application | 沈阳药科大学 | 2022-09-20 | — | — | CN | disclosed |
| CN-113004188-A | Indole derivative, preparation method and application | 沈阳药科大学 | 2021-06-22 | — | — | CN | disclosed |