Catechol

Catechol

SCHEMBL28266274

O=Cc1ccco1.Oc1ccccc1O

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.75
MAPT P10636 7/20 0.53
KMT2A Q03164 6/20 0.53
ABCG2 Q9UNQ0 1/20 0.53
HCAR2 Q8TDS4 1/20 0.46
TRIM24 O15164 1/20 0.45
TRIM33 Q9UPN9 1/20 0.45
POLB P06746 6/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
HTT P42858 1/20 0.43
RAB9A P51151 4/20 0.42
MEN1 O00255 4/20 0.42
NPC1 O15118 3/20 0.42
LMNA P02545 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
GAA P10253 1/20 0.42
KDM4E B2RXH2 3/20 0.42
ERN1 O75460 1/20 0.42
RECQL P46063 2/20 0.42
BLM P54132 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Salicyladehyde SCHEMBL8609443 0.89 ALDH1A1 (0.64) ALDH1A1MAPTKMT2AABCG2HCAR2
Pyrogallol SCHEMBL28230748 0.88 ALDH1A1 (0.69) ALDH1A1MAPTKMT2AABCG2HCAR2
Orthocresol SCHEMBL9714232 0.87 ALDH1A1 (0.62) ALDH1A1MAPTKMT2AABCG2HCAR2
2-Chlorophenol SCHEMBL1360878 0.87 ALDH1A1 (0.62) ALDH1A1MAPTKMT2AABCG2HCAR2
Questiomycin B SCHEMBL28199812 0.87 ALDH1A1 (0.62) ALDH1A1MAPTKMT2AABCG2HCAR2
Furfural SCHEMBL10811266 0.87 ALDH1A1 (1.00) ALDH1A1MAPTKMT2AHCAR2POLB
Furfural SCHEMBL20439 0.87
Furfural SCHEMBL626705 0.87 ALDH1A1 (1.00) ALDH1A1MAPTKMT2AHCAR2POLB
Furfural SCHEMBL361094 0.86 ALDH1A1 (0.72) ALDH1A1MAPTKMT2AABCG2HCAR2
Furfural SCHEMBL28215023 0.86 ALDH1A1 (0.72) ALDH1A1MAPTKMT2AABCG2HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110536983-A Ground cushion is washed with enhancement layer MILLIKEN & CO 2019-12-03 CN disclosed
CN-108995254-A A kind of nano-pore heat-resistant composite material and bearing structure co-curing forming method 华东理工大学 2018-12-14 CN disclosed