Orthocresol

Orthocresol

SCHEMBL9714232

Cc1ccccc1O.O=Cc1ccco1

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.62
KMT2A Q03164 8/20 0.46
MAPT P10636 7/20 0.46
ABCG2 Q9UNQ0 1/20 0.46
NPSR1 Q6W5P4 2/20 0.42
POLB P06746 7/20 0.41
L3MBTL1 Q9Y468 3/20 0.41
ALOX12 P18054 1/20 0.41
MEN1 O00255 6/20 0.40
HCAR2 Q8TDS4 1/20 0.40
NPC1 O15118 3/20 0.39
USP2 O75604 1/20 0.39
TSHR P16473 1/20 0.38
TRIM24 O15164 1/20 0.38
TRIM33 Q9UPN9 1/20 0.38
RAB9A P51151 3/20 0.38
LMNA P02545 1/20 0.38
GAA P10253 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HTT P42858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Orthocresol SCHEMBL11307066 0.94 ALDH1A1 (0.55) ALDH1A1KMT2AMAPTABCG2NPSR1
Catechol SCHEMBL28266274 0.87 ALDH1A1 (0.75) ALDH1A1KMT2AMAPTABCG2POLB
O-Xylene SCHEMBL28533407 0.87 ALDH1A1 (0.75) ALDH1A1KMT2AMAPTNPSR1POLB
Furfural SCHEMBL11420310 0.82 ALDH1A1 (0.51) ALDH1A1KMT2AMAPTABCG2NPSR1
Furfural SCHEMBL11537859 0.81
Salicyladehyde SCHEMBL8609443 0.81 ALDH1A1 (0.64) ALDH1A1KMT2AMAPTABCG2POLB
Furfural SCHEMBL28724667 0.80 ALDH1A1 (0.69) ALDH1A1KMT2AMAPTABCG2NPSR1
Pyrogallol SCHEMBL28230748 0.80 ALDH1A1 (0.69) ALDH1A1KMT2AMAPTABCG2POLB
2-Chlorophenol SCHEMBL1360878 0.79 ALDH1A1 (0.62) ALDH1A1KMT2AMAPTABCG2POLB
Furfural SCHEMBL10811266 0.79 ALDH1A1 (1.00) ALDH1A1KMT2AMAPTPOLBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107596932-B Cation exchange membrane and preparation method and application thereof 黑龙江青谷酒庄有限公司 2020-11-17 CN disclosed
EP-0344022-B1 METHODS FOR PRODUCING PHENOL RESIN FOAMS AND FOAMED LAMINATES Bridgestone Corporation (JP) 1992-11-11 EP disclosed
US-5008297-A Low and high molecular weight resoles; adhesion, fire resistant BRIDGESTONE CORPORATION (JP) 1991-04-16 US disclosed
EP-0344022-A1 Methods for producing phenol resin foams and foamed laminates Bridgestone Corporation (JP) 1989-11-29 EP disclosed