Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ATR | Q13535 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KDM6B | O15054 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31584153 | 0.83 | KDM4E (0.58) | ALDH1A1KDM4EGLAGAAKDM4C | |
| SCHEMBL19284336 | 0.83 | KDM4E (0.58) | ALDH1A1KDM4EGLAGAAKDM4C | |
| SCHEMBL26132704 | 0.78 | ALDH1A1 (0.44) | ALDH1A1KDM4EGLAGAARAB9A | |
| SCHEMBL347774 | 0.78 | CYP3A4 (0.40) | ALDH1A1KDM4EGLAGAARAB9A | |
| SCHEMBL23970755 | 0.76 | ALDH1A1 (0.42) | ALDH1A1KDM4EGLAGAARAB9A | |
| SCHEMBL31364268 | 0.76 | KDM4C (0.47) | ALDH1A1KDM4EGLAGAAATR | |
| SCHEMBL17820387 | 0.76 | KDM4E (0.42) | ALDH1A1KDM4EGLAGAARAB9A | |
| SCHEMBL31487718 | 0.76 | ALDH1A1 (0.68) | ALDH1A1KDM4EGLAGAARAB9A | |
| SCHEMBL21056702 | 0.75 | KDM4C (0.53) | ALDH1A1KDM4EGAAKDM4CMAPT | |
| SCHEMBL29749311 | 0.75 | KDM4C (0.53) | ALDH1A1KDM4EGAAKDM4CMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109153646-A | Pyridine dicarboxamide derivatives as bromine structural domain inhibitor | 葛兰素史克知识产权第二有限公司 | 2019-01-04 | — | — | CN | disclosed |