SCHEMBL28267397

SCHEMBL28267397

CN(C)c1cccc2c(S(=O)(=O)C(Cl)C#N)cccc12

nearest known ligand 0.55

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.55
CYP1A2 P05177 1/20 0.50
CYP2C19 P33261 1/20 0.50
HTT P42858 1/20 0.50
HIF1A Q16665 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
EDNRA P25101 9/20 0.48
F2 P00734 3/20 0.48
PRSS1 P07477 3/20 0.48
PRSS2 P07478 3/20 0.48
PRSS3 P35030 3/20 0.48
KMT2A Q03164 1/20 0.48
ATM Q13315 1/20 0.48
KDM4E B2RXH2 1/20 0.43
NSD2 O96028 1/20 0.43
TSHR P16473 1/20 0.43
HSD17B10 Q99714 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1105200 0.79 CA2 (0.65) CA2CYP1A2CYP2C19HTTHIF1A
Acetonitrile SCHEMBL8500753 0.78 CA2 (0.59) CA2CYP1A2CYP2C19HTTHIF1A
SCHEMBL15641730 0.77 CA2 (0.63) CA2CYP1A2CYP2C19HTTHIF1A
SCHEMBL28337330 0.77 CA2 (0.55) CA2CYP1A2CYP2C19HTTHIF1A
SCHEMBL7558142 0.76 CA2 (0.61) CA2CYP1A2CYP2C19HTTHIF1A
SCHEMBL6046339 0.76 CA2 (0.61) CA2CYP1A2CYP2C19HTTHIF1A
SCHEMBL10344363 0.75 CA2 (0.69) CA2CYP1A2CYP2C19HTTHIF1A
SCHEMBL21283 0.75 CA2 (0.69) CA2CYP1A2CYP2C19HTTHIF1A
SCHEMBL563863 0.75 CA2 (0.69) CA2CYP1A2CYP2C19HTTHIF1A
SCHEMBL29429225 0.75 CA2 (0.69) CA2CYP1A2CYP2C19HTTHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111983044-B Detection method for analyzing steroid hormone based on double-derivative treatment 中国科学院大连化学物理研究所 2023-04-11 CN claimed
CN-115902021-A Method for quantifying dipeptide in white spirit based on dansylation and liquid chromatography-mass spectrometry 贵州茅台酒股份有限公司 2023-04-04 CN claimed
CN-114624343-B Method for relatively quantifying 45 inflammations and immune metabolites in serum 中国科学院大连化学物理研究所 2023-01-24 CN claimed
CN-115201340-A Method for detecting gamma-aminobutyric acid in plant-based food and dairy products 内蒙古伊利实业集团股份有限公司 2022-10-18 CN claimed
CN-111983044-A Detection method for analyzing steroid hormone based on double-derivative treatment 中国科学院大连化学物理研究所 2020-11-24 CN claimed
CN-111721853-A Method for detecting catecholamine substances in blood plasma by using liquid chromatography tandem mass spectrometry 浙江湖州三体生物科技有限公司 2020-09-29 CN claimed
CN-117907470-A Device and method for rapidly detecting metformin in health-care product 桂林医学院 2024-04-19 CN disclosed
CN-111983044-B Detection method for analyzing steroid hormone based on double-derivative treatment 中国科学院大连化学物理研究所 2023-04-11 CN disclosed
CN-115902021-A Method for quantifying dipeptide in white spirit based on dansylation and liquid chromatography-mass spectrometry 贵州茅台酒股份有限公司 2023-04-04 CN disclosed
CN-115902021-A Method for quantifying dipeptide in white spirit based on dansylation and liquid chromatography-mass spectrometry 贵州茅台酒股份有限公司 2023-04-04 CN disclosed
CN-114624343-B Method for relatively quantifying 45 inflammations and immune metabolites in serum 中国科学院大连化学物理研究所 2023-01-24 CN disclosed
CN-115201340-A Method for detecting gamma-aminobutyric acid in plant-based food and dairy products 内蒙古伊利实业集团股份有限公司 2022-10-18 CN disclosed
CN-115047120-A Dansyl chloride derivatization method for analyzing and detecting dipeptide substances in white spirit Daqu 贵州茅台酒股份有限公司 2022-09-13 CN disclosed
CN-114624343-A Method for relative quantification of 45 inflammations and immune metabolites in serum 中国科学院大连化学物理研究所 2022-06-14 CN disclosed
CN-111983044-A Detection method for analyzing steroid hormone based on double-derivative treatment 中国科学院大连化学物理研究所 2020-11-24 CN disclosed
CN-111721853-A Method for detecting catecholamine substances in blood plasma by using liquid chromatography tandem mass spectrometry 浙江湖州三体生物科技有限公司 2020-09-29 CN disclosed
CN-109187832-A LC-MS/MS measures the method for neo-synephrine concentration and the pre-treating method of sample in blood plasma 华润三九医药股份有限公司 2019-01-11 CN disclosed