Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 6/20 | 0.45 |
| ▸ | IDO1 | P14902 | 3/20 | 0.43 |
| ▸ | GABRP | O00591 | 2/20 | 0.42 |
| ▸ | GABRD | O14764 | 2/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.42 |
| ▸ | GABRE | P78334 | 2/20 | 0.42 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.42 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.42 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.42 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL148082 | 0.77 | BCHE (0.50) | TDO2IDO1GABRPGABRDGABRA1 | |
| SCHEMBL1683250 | 0.76 | ESR1 (0.55) | TDO2IDO1GABRPGABRDGABRA1 | |
| SCHEMBL28847891 | 0.71 | TLR8 (0.50) | ALDH1A1HSD17B10METAP1KIF11TUBB4A | |
| SCHEMBL29259140 | 0.70 | KIF11 (0.45) | TDO2IDO1GABRPGABRDGABRA1 | |
| SCHEMBL409752 | 0.69 | KIF11 (0.55) | TDO2IDO1GABRPGABRDGABRA1 | |
| SCHEMBL29897733 | 0.69 | KIF11 (0.55) | TDO2IDO1GABRPGABRDGABRA1 | |
| SCHEMBL26087436 | 0.66 | TDO2 (0.64) | TDO2IDO1GABRPGABRDGABRA1 | |
| SCHEMBL17094777 | 0.66 | AR (0.58) | TDO2IDO1GABRPGABRDGABRA1 | |
| SCHEMBL13563976 | 0.66 | KIF11 (0.78) | TDO2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL191347 | 0.66 | KIF11 (0.71) | TDO2GABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106366069-B | A kind of preparation method of N- heteroaryl carbazole compound | 浙江工业大学 | 2019-01-08 | — | — | CN | disclosed |