Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | C1R | P00736 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | DEPTOR | Q8TB45 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL55516 | 0.97 | NPC1 (0.48) | NPC1KMT2AMAPTRAB9AMEN1 | |
| SCHEMBL55517 | 0.97 | NPC1 (0.48) | NPC1KMT2AMAPTRAB9AMEN1 | |
| SCHEMBL162884 | 0.97 | NPC1 (0.48) | NPC1KMT2AMAPTRAB9AMEN1 | |
| Pyrithione SCHEMBL11635598 | 0.83 | NPC1 (0.36) | NPC1KMT2AMAPTRAB9AMEN1 | |
| SCHEMBL28269070 | 0.81 | MAPT (0.36) | NPC1KMT2AMAPTRAB9AMEN1 | |
| SCHEMBL27481993 | 0.73 | NPC1 (0.47) | NPC1KMT2AMAPTRAB9AMEN1 | |
| SCHEMBL166219 | 0.72 | ALDH1A1 (0.42) | NPC1KMT2AMAPTRAB9AMEN1 | |
| SCHEMBL9056490 | 0.72 | ALDH1A1 (0.42) | NPC1KMT2AMAPTRAB9AMEN1 | |
| SCHEMBL11700142 | 0.69 | MAPT (0.43) | NPC1KMT2AMAPTRAB9AMEN1 | |
| SCHEMBL11696290 | 0.69 | MAPT (0.45) | NPC1KMT2AMAPTRAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109169678-A | Bactericide and composition thereof | 侨昌现代农业有限公司 | 2019-01-11 | — | — | CN | disclosed |