Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 3/20 | 0.52 |
| ▸ | HTR2B | P41595 | 3/20 | 0.52 |
| ▸ | HTR2C | P28335 | 2/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.50 |
| ▸ | DRD3 | P35462 | 2/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL249435 | 0.83 | HTR2A (0.59) | PPARAHTR2AHTR2BHTR2CADRA2C | |
| SCHEMBL5095202 | 0.81 | PPARA (0.64) | PPARAHTR2AHTR2BHTR2CADRA2C | |
| Hydrochloric Acid SCHEMBL5095405 | 0.80 | PPARA (0.63) | PPARAHTR2AHTR2BHTR2CADRA2C | |
| SCHEMBL5095404 | 0.80 | HTR2A (0.55) | PPARAHTR2AHTR2BHTR2CADRA2C | |
| SCHEMBL28268256 | 0.79 | ALDH1A1 (0.59) | MAPTCYP3A4CYP1A2CYP2C9CHRM3 | |
| SCHEMBL20543990 | 0.75 | HTR2A (0.60) | HTR2AHTR2BHTR2CADRA2CSLC6A4 | |
| SCHEMBL6714650 | 0.75 | HTR2A (0.55) | PPARAHTR2AHTR2BHTR2CADRA2C | |
| SCHEMBL30589450 | 0.75 | HTR2A (0.55) | PPARAHTR2AHTR2BHTR2CADRA2C | |
| SCHEMBL11743685 | 0.74 | HTR2A (0.55) | HTR2AHTR2BHTR2CADRA2CSLC6A4 | |
| SCHEMBL5558144 | 0.74 | THRB (0.51) | PPARAHTR2AHTR2BHTR2CMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109153667-A | Novel potassium channel inhibitor | 阿塞西翁制药公司 | 2019-01-04 | — | — | CN | disclosed |