Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | MIF | P14174 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28269918 | 0.78 | ALDH1A1 (0.50) | SMN1; SMN2POLBLMNAMAPTHPGD | |
| SCHEMBL3572406 | 0.77 | LMNA (0.51) | SMN1; SMN2LMNAMAPTKDM4ECYP1A2 | |
| SCHEMBL10509566 | 0.77 | SMN1; SMN2 (0.75) | SMN1; SMN2POLBHSD17B10NPSR1LMNA | |
| SCHEMBL7406459 | 0.75 | SMN1; SMN2 (0.72) | SMN1; SMN2POLBHSD17B10NPSR1LMNA | |
| SCHEMBL323801 | 0.75 | POLB (1.00) | SMN1; SMN2POLBHSD17B10NPSR1LMNA | |
| SCHEMBL5520675 | 0.75 | SMN1; SMN2 (0.72) | SMN1; SMN2POLBHSD17B10NPSR1LMNA | |
| SCHEMBL15391794 | 0.74 | SMN1; SMN2 (0.70) | SMN1; SMN2POLBHSD17B10NPSR1LMNA | |
| SCHEMBL28414879 | 0.74 | SMN1; SMN2 (0.70) | SMN1; SMN2POLBHSD17B10NPSR1LMNA | |
| SCHEMBL9203434 | 0.74 | SMN1; SMN2 (0.70) | SMN1; SMN2POLBHSD17B10NPSR1LMNA | |
| Methyl Alcohol SCHEMBL27939411 | 0.74 | POLB (0.96) | SMN1; SMN2POLBHSD17B10NPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109153655-B | Novel N-acylurea derivatives and compositions comprising the same for preventing or treating cardiovascular diseases | 高丽大学校产学协力团 | 2022-09-30 | — | — | CN | disclosed |
| CN-109153655-A | For preventing or treating the novel N- acyl urea derivatives of cardiovascular disease and comprising its composition | 高丽大学校产学协力团 | 2019-01-04 | — | — | CN | disclosed |