SCHEMBL2827008

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2821991	0.89	TOP2A (0.43)	TOP2ANPC1RAB9ASMN1; SMN2KDM4E
	SCHEMBL2826834	0.81	TOP2A (0.46)	TOP2ANPC1RAB9ASMN1; SMN2KDM4E
	SCHEMBL2822676	0.75	XDH (0.61)	TOP2ANPC1RAB9ASMN1; SMN2KDM4E
	SCHEMBL2823751	0.74	TOP2A (0.45)	TOP2ANPC1RAB9ASMN1; SMN2ALDH1A1
	SCHEMBL2823778	0.73	PTPN1 (0.46)	TOP2ANPC1RAB9ASMN1; SMN2HTT
	SCHEMBL2822885	0.71	NPC1 (0.56)	NPC1RAB9ASMN1; SMN2KDM4EALDH1A1
	SCHEMBL2830031	0.71	TOP2A (0.46)	TOP2ANPC1RAB9AGAA
	SCHEMBL13173547	0.70	TOP2A (0.43)	TOP2ANPC1RAB9ASMN1; SMN2ALDH1A1
	SCHEMBL2823835	0.69	TOP2A (0.39)	TOP2A
	SCHEMBL13002114	0.69	TOP2A (0.45)	TOP2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.