SCHEMBL28271128

SCHEMBL28271128

NC(Cc1ccccc1)n1cncc1C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
ALPI P09923 1/20 0.44
PKM P14618 1/20 0.44
PTGS1 P23219 1/20 0.44
XIAP P98170 1/20 0.44
SLC7A5 Q01650 1/20 0.44
CYP1A2 P05177 3/20 0.41
GABRA1 P14867 3/20 0.41
CYP3A4 P08684 2/20 0.41
GABRB2 P47870 2/20 0.41
CYP11B1 P15538 2/20 0.41
CYP11B2 P19099 2/20 0.41
LMNA P02545 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
ABCB11 O95342 1/20 0.41
GABRA2 P47869 1/20 0.41
SLC1A3 P43003 2/20 0.41
SLC1A2 P43004 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11492702 0.72 ALDH1A1 (0.69) ALDH1A1TDP1CYP1A2GABRA1CYP3A4
SCHEMBL1081229 0.71 ALDH1A1 (1.00) ALDH1A1TDP1CYP1A2GABRA1CYP3A4
SCHEMBL1081228 0.71 ALDH1A1 (1.00) ALDH1A1TDP1CYP1A2GABRA1CYP3A4
Pyrrole SCHEMBL11495979 0.71 ALDH1A1 (0.62) ALDH1A1TDP1CYP1A2GABRA1CYP3A4
SCHEMBL3932992 0.70 CYP11B1 (0.56) ALDH1A1TDP1PKMCYP11B1CYP11B2
SCHEMBL11730438 0.70 ALDH1A1 (0.97) ALDH1A1TDP1CYP1A2GABRA1CYP3A4
Hydrochloric Acid SCHEMBL28186334 0.69 CYP11B1 (0.54) ALDH1A1TDP1PKMCYP11B1CYP11B2
SCHEMBL9837208 0.69 ALDH1A1 (0.65) ALDH1A1TDP1CYP1A2GABRA1CYP3A4
SCHEMBL6050066 0.68 GRN (0.46) ALDH1A1TDP1PKMCYP11B1CYP11B2
SCHEMBL6801626 0.68 ALDH1A1 (0.48) ALDH1A1TDP1ALPIPKMPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109206481-A Peptide compound, application thereof and composition containing peptide compound 凯惠科技发展(上海)有限公司 2019-01-15 CN disclosed