Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 7/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27981450 | 0.86 | ALDH1A1 (0.49) | ALDH1A1TDP1MAPK1GABRA1GABRB2 | |
| SCHEMBL25135971 | 0.82 | ALDH1A1 (0.46) | ALDH1A1TDP1MAPK1GABRA1GABRB2 | |
| SCHEMBL11726722 | 0.79 | ALDH1A1 (1.00) | ALDH1A1TDP1MAPK1GABRA1GABRB2 | |
| Hydrochloric Acid SCHEMBL1081962 | 0.78 | ALDH1A1 (0.97) | ALDH1A1TDP1MAPK1GABRA1GABRB2 | |
| SCHEMBL17693020 | 0.76 | ALDH1A1 (0.71) | ALDH1A1TDP1MAPK1GABRA1GABRB2 | |
| SCHEMBL22370231 | 0.76 | ALDH1A1 (0.76) | ALDH1A1TDP1MAPK1GABRA1GABRB2 | |
| SCHEMBL22370234 | 0.76 | ALDH1A1 (0.76) | ALDH1A1TDP1MAPK1GABRA1GABRB2 | |
| SCHEMBL16950285 | 0.76 | ALDH1A1 (0.76) | ALDH1A1TDP1MAPK1GABRA1GABRB2 | |
| Sulfuric Acid SCHEMBL11737786 | 0.74 | ALDH1A1 (0.89) | ALDH1A1TDP1MAPK1GABRA1GABRB2 | |
| SCHEMBL7340516 | 0.74 | ALDH1A1 (0.71) | ALDH1A1TDP1MAPK1GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250353817-A1 | INTERLUKIN-17A INHIBITORS AND USES THEREOF | GILEAD SCIENCES INC (US) | 2025-11-20 | — | — | US | disclosed |
| EP-4408530-A1 | BENZIMIDAZOLES AS MODULATORS OF IL-17 | Janssen Pharmaceutica NV (BE) | 2024-08-07 | — | — | EP | disclosed |
| CN-115884810-A | Imidazopyridazines as IL-17 modulators | 詹森药业有限公司 | 2023-03-31 | — | — | CN | disclosed |
| WO-2023049888-A1 | BENZIMIDAZOLES AS MODULATORS OF IL-17 | JANSSEN PHARMACEUTICA NV (BE) | 2023-03-30 | — | — | WO | disclosed |
| EP-4143195-A1 | IMIDAZOPYRIDAZINES AS MODULATORS OF IL-17 | Janssen Pharmaceutica NV (BE) | 2023-03-08 | — | — | EP | disclosed |
| EP-0191514-B1 | IMIDAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS FUNGICIDES | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1991-04-03 | — | — | EP | disclosed |
| EP-0191514-A1 | Imidazole derivatives, their preparation and their use as fungicides | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1986-08-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250353817-A1 | INTERLUKIN-17A INHIBITORS AND USES THEREOF | IL17A, IL15, IL23R | ALDH1A1 536/4885TDP1 3198/4885MAPK1 656/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.