SCHEMBL28271663

SCHEMBL28271663

CCCCCC(=O)NC(C)C(=O)OCc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.55
KMT2A Q03164 1/20 0.55
ALDH1A1 P00352 1/20 0.53
ASAH1 Q13510 1/20 0.53
ACER2 Q5QJU3 1/20 0.53
EPHX2 P34913 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.50
LPAR1 Q92633 2/20 0.48
LPAR3 Q9UBY5 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28271662 1.00 MEN1 (0.55) MEN1KMT2AALDH1A1ASAH1ACER2
SCHEMBL23617813 0.90 SMN1; SMN2 (0.48) ALDH1A1SMN1; SMN2
SCHEMBL9876469 0.90 ALDH1A1 (0.49) ALDH1A1SMN1; SMN2
SCHEMBL13314953 0.90 ATM (0.49) ALDH1A1SMN1; SMN2
SCHEMBL9876522 0.88 ALDH1A1 (0.49) ALDH1A1SMN1; SMN2
SCHEMBL28270210 0.87 ERAP2 (0.55) MEN1KMT2AALDH1A1ASAH1ACER2
SCHEMBL28270209 0.87 ERAP2 (0.55) MEN1KMT2AALDH1A1ASAH1ACER2
SCHEMBL28252260 0.86 ALDH1A1 (0.53) MEN1KMT2AALDH1A1ASAH1ACER2
SCHEMBL28252259 0.86 ALDH1A1 (0.53) MEN1KMT2AALDH1A1ASAH1ACER2
SCHEMBL30605518 0.85 EPHX2 (0.46) ALDH1A1EPHX2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109081789-A The positive positive hexanoyl fatty acid/amino acid of hexanoyl amino first cyclic amide base of amino, synthesis, activity and application 首都医科大学 2018-12-25 CN disclosed