Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.45 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9876469 | 0.97 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2ATMTDP1MAPT | |
| SCHEMBL23617813 | 0.89 | SMN1; SMN2 (0.48) | ALDH1A1SMN1; SMN2ATMTDP1MAPT | |
| SCHEMBL28271662 | 0.88 | MEN1 (0.55) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL28271663 | 0.88 | MEN1 (0.55) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL30605518 | 0.86 | EPHX2 (0.46) | ALDH1A1SMN1; SMN2ATMTDP1MAPT | |
| SCHEMBL13314953 | 0.86 | ATM (0.49) | ALDH1A1SMN1; SMN2ATMTDP1MAPT | |
| SCHEMBL9775264 | 0.86 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2ATML3MBTL1 | |
| SCHEMBL10099537 | 0.82 | GAA (0.52) | ALDH1A1ATMTDP1MAPTL3MBTL1 | |
| SCHEMBL13296295 | 0.82 | GAA (0.52) | ALDH1A1ATMTDP1MAPTL3MBTL1 | |
| SCHEMBL29233276 | 0.82 | ATM (0.51) | ALDH1A1ATMTDP1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5043340-A | Antibody-drug conjugates; antitumor agents; leukemia; cancer | ELI LILLY AND COMPANY (US) | 1991-08-27 | — | — | US | disclosed |