SCHEMBL28273630

SCHEMBL28273630

C=C(C)C(=O)OCCN(CC)CC.C=C(C)C(=O)OCCN(CC)CC

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.55
TSHR P16473 5/20 0.53
CYP2D6 P10635 3/20 0.44
LMNA P02545 3/20 0.44
CYP1A2 P05177 2/20 0.44
MAOA P21397 1/20 0.44
HTR3A P46098 1/20 0.44
HRH3 Q9Y5N1 1/20 0.44
CYP3A4 P08684 2/20 0.42
BLM P54132 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
ALDH1A1 P00352 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
CHRM2 P08172 4/20 0.41
CHRM1 P11229 3/20 0.41
CHRM3 P20309 3/20 0.41
SCN1A P35498 3/20 0.41
SCN2A Q99250 3/20 0.41
SCN3A Q9NY46 3/20 0.41
CHRM4 P08173 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14874 1.00 THRB (0.55) THRBTSHRCYP2D6LMNACYP1A2
SCHEMBL22684899 0.98 THRB (0.53) THRBTSHRCYP2D6LMNACYP1A2
SCHEMBL9800939 0.98 THRB (0.53) THRBTSHRCYP2D6LMNACYP1A2
Hydrochloric Acid SCHEMBL2847352 0.98 THRB (0.53) THRBTSHRCYP2D6LMNACYP1A2
Chloromethane SCHEMBL1128072 0.96 THRB (0.52) THRBTSHRCYP2D6LMNACYP1A2
Acetic Acid SCHEMBL10336380 0.96 THRB (0.52) THRBTSHRCYP2D6LMNACYP1A2
SCHEMBL10697522 0.96 THRB (0.55) THRBTSHRCYP2D6LMNACYP1A2
Boric Acid SCHEMBL8763859 0.94 THRB (0.50) THRBTSHRCYP2D6LMNACYP1A2
SCHEMBL10598725 0.94 THRB (0.55) THRBTSHRCYP2D6LMNACYP1A2
SCHEMBL28477901 0.94 THRB (0.50) THRBTSHRCYP2D6LMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109444276-A A kind of gas-chromatography packed column and its preparation method and application 兰州东立龙信息技术有限公司 2019-03-08 CN disclosed
CN-109158095-A A kind of filling column packing and preparation method thereof 兰州东立龙信息技术有限公司 2019-01-08 CN disclosed