Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA known ✓ | P21397 | 1/20 | 0.42 |
| ▸ | HTR3A known ✓ | P46098 | 1/20 | 0.42 |
| ▸ | HRH3 known ✓ | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | SCN1A known ✓ | P35498 | 1/20 | 0.41 |
| ▸ | SCN2A known ✓ | Q99250 | 1/20 | 0.41 |
| ▸ | SCN3A known ✓ | Q9NY46 | 1/20 | 0.41 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 known ✓ | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 known ✓ | P08912 | 1/20 | 0.41 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 5/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28273630 | 0.98 | THRB (0.55) | THRBTSHRNPSR1CYP3A4BLM | |
| SCHEMBL14874 | 0.98 | THRB (0.55) | THRBTSHRNPSR1CYP3A4BLM | |
| SCHEMBL22684899 | 0.96 | THRB (0.53) | THRBTSHRNPSR1CYP3A4BLM | |
| SCHEMBL9800939 | 0.96 | THRB (0.53) | THRBTSHRNPSR1CYP3A4BLM | |
| Chloromethane SCHEMBL1128072 | 0.94 | THRB (0.52) | THRBTSHRNPSR1CYP3A4BLM | |
| Acetic Acid SCHEMBL10336380 | 0.94 | THRB (0.52) | THRBTSHRNPSR1CYP3A4BLM | |
| SCHEMBL10697522 | 0.94 | THRB (0.55) | THRBTSHRNPSR1CYP3A4BLM | |
| Boric Acid SCHEMBL8763859 | 0.93 | THRB (0.50) | THRBTSHRNPSR1CYP3A4BLM | |
| SCHEMBL10598725 | 0.93 | THRB (0.55) | THRBTSHRNPSR1CYP3A4BLM | |
| SCHEMBL28477901 | 0.93 | THRB (0.50) | THRBTSHRNPSR1CYP3A4BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250154401-A1 | REDUCED-POLYMER-LOADING, HIGH-TEMPERATURE FRACTURING FLUIDS AND METHODS AND SYSTEMS RELATED THERETO | SAUDI ARABIAN OIL COMPANY (SA) | 2025-05-15 | — | — | US | claimed |
| US-12209218-B2 | Reduced-polymer-loading, high-temperature fracturing fluids and methods and systems related thereto | SAUDI ARABIAN OIL COMPANY (SA) | 2025-01-28 | — | — | US | claimed |
| US-20240425748-A1 | REDUCED-POLYMER-LOADING, HIGH-TEMPERATURE FRACTURING FLUIDS AND METHODS AND SYSTEMS RELATED THERETO | SAUDI ARABIAN OIL COMPANY (SA) | 2024-12-26 | — | — | US | claimed |
| WO-2024263632-A1 | REDUCED-POLYMER-LOADING, HIGH-TEMPERATURE FRACTURING FLUIDS AND METHODS AND SYSTEMS RELATED THERETO | SAUDI ARABIAN OIL COMPANY (SA) | 2024-12-26 | — | — | WO | claimed |
| CN-115926663-A | Photo-thermal dual-debonding adhesive and preparation method thereof | 上海固柯胶带科技有限公司 | 2023-04-07 | — | — | CN | claimed |
| US-9119849-B2 | Substituted guar protein extracts and production/applications thereof | RHODIA CHIMIE (FR) | 2015-09-01 | — | — | US | claimed |
| US-20100093933-A1 | Substituted Guar Protein Extracts and Production/Applications Thereof | RHODIA CHIMIE (FR) | 2010-04-15 | — | — | US | claimed |
| US-20250154401-A1 | REDUCED-POLYMER-LOADING, HIGH-TEMPERATURE FRACTURING FLUIDS AND METHODS AND SYSTEMS RELATED THERETO | SAUDI ARABIAN OIL COMPANY (SA) | 2025-05-15 | — | — | US | disclosed |
| US-12209218-B2 | Reduced-polymer-loading, high-temperature fracturing fluids and methods and systems related thereto | SAUDI ARABIAN OIL COMPANY (SA) | 2025-01-28 | — | — | US | disclosed |
| US-20240425748-A1 | REDUCED-POLYMER-LOADING, HIGH-TEMPERATURE FRACTURING FLUIDS AND METHODS AND SYSTEMS RELATED THERETO | SAUDI ARABIAN OIL COMPANY (SA) | 2024-12-26 | — | — | US | disclosed |
| WO-2024263632-A1 | REDUCED-POLYMER-LOADING, HIGH-TEMPERATURE FRACTURING FLUIDS AND METHODS AND SYSTEMS RELATED THERETO | SAUDI ARABIAN OIL COMPANY (SA) | 2024-12-26 | — | — | WO | disclosed |
| US-20160235645-A1 | GUAR PROTEIN EXTRACTS AND COMPOSITIONS COMPRISED THEREOF AS SURFACE TREATING AND/OR MODIFYING AGENTS | RHODIA CHIMIE (FR) | 2016-08-18 | — | — | US | disclosed |
| US-9119849-B2 | Substituted guar protein extracts and production/applications thereof | RHODIA CHIMIE (FR) | 2015-09-01 | — | — | US | disclosed |
| US-4981936-A | CATIONIC FLOCCULANTS | POLYPURE, INC. (US) | 1991-01-01 | — | — | US | disclosed |
| EP-0383358-A2 | Light-sensitive material containing silver halide reducing agent and polymerizable compound | FUJI PHOTO FILM CO., LTD. (JP) | 1990-08-22 | — | — | EP | disclosed |
| US-4767017-A | EPOXY RESIN MATRIX REINFORCED WITH POLYAMIDE FILAMENTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-08-30 | — | — | US | disclosed |
| US-4678821-A | ARAMID FIBER COATED WITH ADHESION MODIFIER IN POLYMER MATRIX | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-07-07 | — | — | US | disclosed |
| US-4618554-A | AN AMINOALKYL (METH)ACRYLATE | TOYO INK MFG. CO., LTD. (JP) | 1986-10-21 | — | — | US | disclosed |
| US-4480025-A | Water reservoir layers in bleach-fix sheets | EASTMAN KODAK COMPANY (US) | 1984-10-30 | — | — | US | disclosed |
| EP-0117165-A2 | Bleach-fix sheet | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1984-08-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100093933-A1 | Substituted Guar Protein Extracts and Production/Applications Thereof | CUTA, HIRA, PMP22 | MAOA 2683/4885HTR3A 4411/4885HRH3 1325/4885 |
| US-20160235645-A1 | GUAR PROTEIN EXTRACTS AND COMPOSITIONS COMPRISED THEREOF AS SURFACE TREATING AND/OR MODIFYING AGENTS | CUTA, GLA, PAG1 | MAOA 1719/4885HTR3A 4253/4885HRH3 1839/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.