Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 2/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | PAM | P19021 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | ALPI | P09923 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11906139 | 0.90 | LTA4H (0.44) | LTA4HMMP2ITGB3ITGA2BDPP8 | |
| Acetic Acid SCHEMBL27970702 | 0.86 | ATM (0.42) | LTA4HMMP2PTGS1ITGB3ITGA2B | |
| SCHEMBL7775125 | 0.86 | GSR (0.50) | LTA4HMMP2ITGB3ITGA2BDPP8 | |
| SCHEMBL7775127 | 0.86 | GSR (0.50) | LTA4HMMP2ITGB3ITGA2BDPP8 | |
| Phenylacetic Acid SCHEMBL1702338 | 0.83 | AKR1B1 (0.55) | AKR1B1LTA4HMMP2PTGS1ABCC4 | |
| Phenylacetic Acid SCHEMBL16975021 | 0.83 | AKR1B1 (0.55) | AKR1B1LTA4HMMP2PTGS1ABCC4 | |
| Phenethylamine SCHEMBL13518821 | 0.81 | LTA4H (0.44) | AKR1B1LTA4HSRD5A2FFAR1 | |
| Phenethylamine SCHEMBL13517918 | 0.81 | LTA4H (0.44) | AKR1B1LTA4HSRD5A2FFAR1 | |
| SCHEMBL28120129 | 0.81 | ATM (0.44) | LTA4HPTGS1DPP8DPP7ALPI | |
| SCHEMBL7874885 | 0.79 | LTA4H (0.41) | LTA4HMMP2ITGB3ITGA2BDPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106810464-B | L-ornithine phenyl acetate and preparation method thereof | 欧塞拉治疗有限公司 | 2019-01-22 | — | — | CN | disclosed |