Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | GSR | P00390 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11906139 | 0.88 | LTA4H (0.44) | LTA4HDPP8DPP7DPP9MMP2 | |
| SCHEMBL23111345 | 0.84 | LTA4H (0.43) | LTA4HGSRSLC1A3 | |
| Acetic Acid SCHEMBL27970702 | 0.84 | ATM (0.42) | LTA4HDPP8DPP7DPP9MMP2 | |
| SCHEMBL7775125 | 0.83 | GSR (0.50) | LTA4HDPP8DPP7DPP9MMP2 | |
| SCHEMBL7775127 | 0.83 | GSR (0.50) | LTA4HDPP8DPP7DPP9MMP2 | |
| SCHEMBL23111343 | 0.82 | LTA4H (0.40) | LTA4HSLC1A3ATML3MBTL1 | |
| SCHEMBL23111344 | 0.82 | LTA4H (0.40) | LTA4HSLC1A3ATML3MBTL1 | |
| SCHEMBL7391550 | 0.81 | LTA4H (0.48) | LTA4HDPP8DPP7MMP2TDP1 | |
| SCHEMBL28333235 | 0.80 | LTA4H (0.41) | LTA4HTDP1KMT2ASLC1A3ATM | |
| Phenylacetic Acid SCHEMBL28273739 | 0.79 | AKR1B1 (0.46) | LTA4HDPP8DPP7DPP9MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310178-B1 | AS THE N-TERMINAL RESIDUE OF BIOLOGICALLY ACTIVE PEPTIDES, E.G, THYROTROPIN RELEASING HORMONE (BY REPLACING THE N-TERMINAL PYROGLUTAMYL GROUP); IMPARTING INCREASED RESISTANCE TO PROTEOLYTIC DIGESTION | SOLVAY, S.A. (BE) | 2001-10-30 | — | — | US | disclosed |