Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1066978 | 0.90 | PSEN1 (0.41) | TSHRCTSLCTSBCTSKOPRM1 | |
| SCHEMBL1857531 | 0.90 | PSEN1 (0.41) | TSHRCTSLCTSBCTSKOPRM1 | |
| SCHEMBL1061761 | 0.90 | PSEN1 (0.41) | TSHRCTSLCTSBCTSKOPRM1 | |
| SCHEMBL4440940 | 0.89 | PSEN1 (0.40) | TSHRCTSLCTSBCTSKOPRM1 | |
| SCHEMBL2767536 | 0.89 | PSEN1 (0.40) | TSHRCTSLCTSBCTSKOPRM1 | |
| SCHEMBL12077141 | 0.89 | PSEN1 (0.40) | TSHRCTSLCTSBCTSKOPRM1 | |
| SCHEMBL10955709 | 0.87 | CTSL (0.41) | TSHRCTSLCTSBCTSKOPRM1 | |
| SCHEMBL7668354 | 0.83 | TSHR (0.48) | TSHRCTSLCTSBCTSKOPRM1 | |
| SCHEMBL11427031 | 0.79 | PSEN1 (0.41) | TSHRCTSLCTSBCTSKOPRM1 | |
| SCHEMBL11440021 | 0.77 | TSHR (0.46) | TSHRCTSLCTSBCTSKOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117813293-A | Urea derivatives useful for the treatment of cancer | 蝎子疗法股份有限公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-109311857-A | Pyrimidin-2-ylamino-1H-pyrazoles as LRRK2 inhibitors for the treatment of neurodegenerative disorders | 戴纳立制药公司 | 2019-02-05 | — | — | CN | disclosed |