Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 4/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23552908 | 0.89 | HDAC3 (0.35) | ZDHHC7KMT2AMEN1GAA | |
| SCHEMBL23552907 | 0.89 | HDAC3 (0.35) | ZDHHC7KMT2AMEN1GAA | |
| SCHEMBL17754726 | 0.86 | ZDHHC7 (0.47) | TSHRZDHHC7CA12CA14CA2 | |
| SCHEMBL868172 | 0.83 | ZDHHC7 (0.55) | TSHRZDHHC7CA12CA14CA2 | |
| SCHEMBL12358675 | 0.83 | ZDHHC7 (0.55) | TSHRZDHHC7CA12CA14CA2 | |
| SCHEMBL29589922 | 0.83 | ZDHHC7 (0.55) | TSHRZDHHC7CA12CA14CA2 | |
| SCHEMBL8785206 | 0.82 | ZDHHC7 (0.39) | ZDHHC7CA12CA14CA2CA1 | |
| SCHEMBL9101944 | 0.81 | GABRP (0.38) | TSHRZDHHC7SLC1A1KMT2AMEN1 | |
| SCHEMBL13613730 | 0.80 | TSHR (0.43) | TSHRCA12CA14CA2CA1 | |
| SCHEMBL19691931 | 0.80 | TSHR (0.43) | TSHRCA12CA14CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109438267-B | Bifunctional complexing agent containing tetraphenylethylene and preparation method and application thereof | 首都医科大学 | 2021-06-01 | — | — | CN | disclosed |
| CN-109438267-A | A kind of bi-functional complexing agent and its preparation method and application containing tetraphenylethylene | 首都医科大学 | 2019-03-08 | — | — | CN | disclosed |