SCHEMBL868172

SCHEMBL868172

COC(=O)CCC(Br)C(=O)OC

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ZDHHC7 Q9NXF8 1/20 0.55
TSHR P16473 4/20 0.50
SLC1A1 P43005 1/20 0.42
KMT2A Q03164 2/20 0.39
MEN1 O00255 1/20 0.39
LMNA P02545 3/20 0.38
CA12 O43570 2/20 0.38
CA14 Q9ULX7 1/20 0.38
KDM4E B2RXH2 1/20 0.38
HSD17B10 Q99714 2/20 0.36
ALDH1A1 P00352 2/20 0.36
MAPT P10636 1/20 0.36
HTT P42858 1/20 0.36
MGAM O43451 1/20 0.36
GAA P10253 1/20 0.36
SI P14410 1/20 0.36
MGAM2 Q2M2H8 1/20 0.36
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
CA9 Q16790 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29589922 1.00 ZDHHC7 (0.55) ZDHHC7TSHRSLC1A1KMT2AMEN1
SCHEMBL12358675 1.00 ZDHHC7 (0.55) ZDHHC7TSHRSLC1A1KMT2AMEN1
SCHEMBL9154081 0.88 ZDHHC7 (0.61) ZDHHC7TSHRSLC1A1KMT2AMEN1
SCHEMBL10929017 0.84 ZDHHC7 (0.68) ZDHHC7TSHRKMT2ALMNAALDH1A1
SCHEMBL5965786 0.84 ZDHHC7 (0.65) ZDHHC7TSHRKMT2ACA12CA14
SCHEMBL1415237 0.84 ZDHHC7 (0.65) ZDHHC7TSHRKMT2ACA12CA14
SCHEMBL28274656 0.83 TSHR (0.41) ZDHHC7TSHRSLC1A1KMT2AMEN1
SCHEMBL17754726 0.83 ZDHHC7 (0.47) ZDHHC7TSHRKMT2AMEN1CA12
SCHEMBL5556511 0.83 ZDHHC7 (0.55) ZDHHC7TSHRSLC1A1KDM4ECA1
SCHEMBL30081398 0.83 ZDHHC7 (0.55) ZDHHC7TSHRSLC1A1KDM4ECA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4722203-A1 3,4-DIHYDROPHTHALAZIN-1(2H)-ONE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF Academy of Military Medical Sciences (CN) 2026-04-08 EP claimed
WO-2024251080-A1 3,4-DIHYDROPHTHALAZIN-1(2H)-ONE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF 中国人民解放军军事科学院军事医学研究院 2024-12-12 WO claimed
CN-117025117-B High-temperature-resistant and deformation-resistant chip epoxy adhesive film and preparation method thereof 青岛德聚胶接技术有限公司 2024-09-24 CN claimed
CN-117025117-A High-temperature-resistant and deformation-resistant chip epoxy adhesive film and preparation method thereof 青岛德聚胶接技术有限公司 2023-11-10 CN claimed
CN-116655591-A 3, 4-dihydro phthalazine-1 (2H) -ketone derivative and preparation method and application thereof 中国人民解放军军事科学院军事医学研究院 2023-08-29 CN claimed
US-20260103468-A1 FUSED RING COMPOUND, PHARMACEUTICAL COMPOSITION, AND USE THEREOF HAINAN SIMCERE ZAIMING PHARMACEUTICAL CO., LTD. (CN) 2026-04-16 US disclosed
US-20260098043-A1 POLYCYCLIC COMPOUND AND USE THEREOF HAINAN SIMCERE ZAIMING PHARMECEUTICAL CO LTD (CN) 2026-04-09 US disclosed
EP-4722203-A1 3,4-DIHYDROPHTHALAZIN-1(2H)-ONE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF Academy of Military Medical Sciences (CN) 2026-04-08 EP disclosed
EP-4713329-A1 NEW CONTRAST AGENTS FOR USE IN DIAGNOSTIC IMAGING Bayer Aktiengesellschaft (DE) 2026-03-25 EP disclosed
US-12528814-B2 Bifunctional degraders of interleukin-1 receptor-associated kinases and therapeutic use thereof NURIX THERAPEUTICS, INC. (US) 2026-01-20 US disclosed
US-20250367129-A1 Lipid Compounds and Uses Thereof PFIZER (US) 2025-12-04 US disclosed
US-20250360219-A1 CEREBLON LIGANDS AND BIFUNCTIONAL COMPOUNDS COMPRISING THE SAME ARVINAS OPERATIONS INC (US) 2025-11-27 US disclosed
EP-0661279-B1 Polyaminated ligands, metal complexes, process for their preparation and diagnostic and therapeutic applications GUERBET SA (FR) 2001-03-07 EP disclosed
US-6187285-B1 IN PARTICULAR MAGNETIC RESONANCE IMAGING (MRI) FOR MAGNETIC CATIONS. GUERBET (FR) 2001-02-13 US disclosed
US-5919432-A Polyaminated ligands and metal complexes thereof GUERBET S.A. (FR) 1999-07-06 US disclosed
US-5886158-A Metal complexes of polyamino oxides, and their utilization in diagnostic imaging GUERBET S.A. (FR) 1999-03-23 US disclosed
CN-1189778-A Metal complexes of polyaminoacids, and their utilization in diagnostic imaging GUERBET SA (FR) 1998-08-05 CN disclosed
US-5712389-A Polyaminated ligands and metal complexes thereof GUERBET S.A. (FR) 1998-01-27 US disclosed
EP-0661279-A1 Polyaminated ligands, metal complexes, process for their preparation and diagnostic and therapeutic applications GUERBET S.A. (FR) 1995-07-05 EP disclosed
EP-0480745-A2 Substituted dihydrothieno-thiophene-2-sulfonamides and dioxides thereof MERCK & CO. INC. (US) 1992-04-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250360219-A1 CEREBLON LIGANDS AND BIFUNCTIONAL COMPOUNDS COMPRISING THE SAME CRBN, CBL, MDM2 ZDHHC7 3500/4885TSHR 3772/4885SLC1A1 3888/4885
US-12528814-B2 Bifunctional degraders of interleukin-1 receptor-associated kinases and therapeutic use thereof IRAK1, IRAK2, IRAK3 ZDHHC7 2160/4885TSHR 1625/4885SLC1A1 4118/4885
US-20260098043-A1 POLYCYCLIC COMPOUND AND USE THEREOF H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, NR3C2, NR3C1 ZDHHC7 2213/4885TSHR 220/4885SLC1A1 3048/4885
US-20260103468-A1 FUSED RING COMPOUND, PHARMACEUTICAL COMPOSITION, AND USE THEREOF NR3C2, CYP11B1, CYP11B2 ZDHHC7 2356/4885TSHR 384/4885SLC1A1 1766/4885
US-20250367129-A1 Lipid Compounds and Uses Thereof POLN, PHOSPHO1, NPC1 ZDHHC7 490/4885TSHR 3471/4885SLC1A1 1824/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.