Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | LPL | P06858 | 1/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.31 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.31 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.31 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.31 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | HPGDS | O60760 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28324463 | 0.81 | ADRA2A (0.35) | ADRA2AADRA2BADRA2CHDAC1HDAC6 | |
| SCHEMBL29580407 | 0.77 | CA2 (0.48) | ADRA2AADRA2BADRA2CHDAC1HDAC6 | |
| SCHEMBL116584 | 0.77 | CA2 (0.48) | ADRA2AADRA2BADRA2CHDAC1HDAC6 | |
| Water SCHEMBL303268 | 0.75 | CA2 (0.46) | ADRA2AADRA2BADRA2CHDAC1HDAC6 | |
| SCHEMBL26792877 | 0.75 | ADRA2A (0.39) | ADRA2AADRA2BADRA2CHDAC1HDAC6 | |
| Water SCHEMBL29951952 | 0.75 | CA2 (0.46) | ADRA2AADRA2BADRA2CHDAC1HDAC6 | |
| SCHEMBL24220348 | 0.74 | KMT2A (0.33) | ADRA2AADRA2BADRA2CHDAC1HDAC6 | |
| SCHEMBL532324 | 0.74 | KMT2A (0.36) | ADRA2AADRA2BADRA2CHDAC1HDAC6 | |
| SCHEMBL29951520 | 0.74 | ADRA2A (0.38) | ADRA2AADRA2BADRA2CHDAC1HDAC6 | |
| SCHEMBL27965000 | 0.73 | CA2 (0.54) | CA2LPLLIPGORAI1ORAI2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311887-A | Pyrazolo [1,5-a] pyrimidine radicals benzamide compound and they treatment medical conditions in purposes | 溶酶体治疗股份有限公司 | 2019-02-05 | — | — | CN | disclosed |