Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 4/20 | 0.48 |
| ▸ | AHR | P35869 | 3/20 | 0.44 |
| ▸ | MAOA | P21397 | 10/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.37 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.37 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.37 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.37 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.37 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.37 |
| ▸ | FXYD2 | P54710 | 1/20 | 0.37 |
| ▸ | ATP1A4 | Q13733 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21130060 | 0.76 | TTR (0.53) | TTRAHRMAOA | |
| SCHEMBL20346601 | 0.75 | TTR (0.51) | TTRAHRMAOAEGFR | |
| SCHEMBL19802418 | 0.73 | AHR (0.45) | TTRAHRMAOA | |
| SCHEMBL28469112 | 0.73 | GLA (0.58) | TTRAHRATP1A1ATP1B1ATP1A3 | |
| SCHEMBL8815383 | 0.72 | TTR (0.65) | TTRAHRMAOAEGFRATP1A1 | |
| SCHEMBL31193433 | 0.72 | MAOA (0.64) | TTRAHRMAOA | |
| SCHEMBL6570481 | 0.72 | MAOA (0.64) | TTRAHRMAOA | |
| SCHEMBL19642257 | 0.71 | TTR (0.64) | TTRAHRMAOA | |
| SCHEMBL19641739 | 0.71 | TTR (0.57) | TTRAHRMAOAEGFR | |
| SCHEMBL29548235 | 0.71 | TTR (0.57) | TTRAHRMAOAEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311860-A | For treating or preventing the Xanthone derivative of hepatitis type B virus disease | 豪夫迈·罗氏有限公司 | 2019-02-05 | — | — | CN | disclosed |