SCHEMBL28275232

SCHEMBL28275232

CCOC(=O)c1ccc(OC)cc1C(=O)OCC

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 7/20 0.60
ALDH1A1 P00352 6/20 0.60
KDM4E B2RXH2 5/20 0.60
TSHR P16473 1/20 0.58
CA12 O43570 3/20 0.57
CA2 P00918 3/20 0.57
CA7 P43166 3/20 0.57
CA9 Q16790 3/20 0.57
CA14 Q9ULX7 3/20 0.57
MAOB P27338 2/20 0.57
GLA P06280 1/20 0.57
CA3 P07451 1/20 0.57
GAA P10253 1/20 0.57
CA4 P22748 1/20 0.57
CA6 P23280 1/20 0.57
NPC1 O15118 5/20 0.54
RAB9A P51151 5/20 0.54
L3MBTL1 Q9Y468 3/20 0.54
LMNA P02545 2/20 0.54
HTT P42858 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25839264 0.95 ALDH1A1 (0.56) HPGDALDH1A1KDM4ETSHRCA12
SCHEMBL27737353 0.95 ALDH1A1 (0.56) HPGDALDH1A1KDM4ETSHRCA12
SCHEMBL2060500 0.92 KDM4E (0.56) HPGDALDH1A1KDM4ETSHRCA12
SCHEMBL24077065 0.90 KDM4E (0.55) HPGDALDH1A1KDM4ETSHRCA12
SCHEMBL3481145 0.88 HPGD (0.58) HPGDALDH1A1KDM4ETSHRCA12
SCHEMBL3481769 0.88 HPGD (0.58) HPGDALDH1A1KDM4ETSHRCA12
SCHEMBL29191709 0.86 MEN1 (0.62) HPGDALDH1A1KDM4ETSHRCA12
SCHEMBL17779153 0.86 CA12 (0.73) HPGDALDH1A1KDM4ECA12CA2
SCHEMBL22852762 0.86 HPGD (0.57) HPGDALDH1A1KDM4ETSHRCA12
SCHEMBL30294848 0.86 HPGD (0.57) HPGDALDH1A1KDM4ETSHRCA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106543314-B The application of catalyst containing ether ester and the catalyst and ether ester in olefin polymerization 中国石油化工股份有限公司 2019-02-19 CN claimed
CN-106543310-B A kind of olefin polymerization catalyst system and its application 中国石油化工股份有限公司 2019-06-28 CN disclosed
CN-106543312-B A kind of olefin polymerization catalyst system and its application 中国石油化工股份有限公司 2019-06-28 CN disclosed
CN-106543313-B A kind of olefin polymerization catalyst system and its application 中国石油化工股份有限公司 2019-06-28 CN disclosed
CN-106543314-B The application of catalyst containing ether ester and the catalyst and ether ester in olefin polymerization 中国石油化工股份有限公司 2019-02-19 CN disclosed