Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.56 |
| ▸ | HPGD | P15428 | 7/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 3/20 | 0.53 |
| ▸ | CA2 | P00918 | 3/20 | 0.53 |
| ▸ | CA7 | P43166 | 3/20 | 0.53 |
| ▸ | CA9 | Q16790 | 3/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | CA3 | P07451 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | CA6 | P23280 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27737353 | 1.00 | ALDH1A1 (0.56) | ALDH1A1KDM4EHPGDCYP1A2CYP2D6 | |
| SCHEMBL28275232 | 0.95 | HPGD (0.60) | ALDH1A1KDM4EHPGDCA12CA2 | |
| SCHEMBL382822 | 0.88 | KDM4E (0.66) | ALDH1A1KDM4EHPGDCYP1A2CYP2D6 | |
| SCHEMBL2060500 | 0.87 | KDM4E (0.56) | ALDH1A1KDM4EHPGDCA12CA2 | |
| SCHEMBL23526071 | 0.86 | KDM4E (0.50) | ALDH1A1KDM4EHPGDCYP1A2CYP2D6 | |
| SCHEMBL24077065 | 0.86 | KDM4E (0.55) | ALDH1A1KDM4EHPGDCA12CA2 | |
| SCHEMBL3481769 | 0.83 | HPGD (0.58) | ALDH1A1KDM4EHPGDCA12CA2 | |
| SCHEMBL3481145 | 0.83 | HPGD (0.58) | ALDH1A1KDM4EHPGDCA12CA2 | |
| SCHEMBL20996786 | 0.82 | KDM4E (0.56) | ALDH1A1KDM4EHPGDCA12CA2 | |
| SCHEMBL11925429 | 0.82 | CA12 (0.56) | ALDH1A1KDM4EHPGDCYP1A2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11702418-B2 | SOS1 inhibitors | Mirati Therapeutics, Inc. (US) | 2023-07-18 | — | — | US | disclosed |
| US-11702418-B2 | SOS1 inhibitors | Mirati Therapeutics, Inc. (US) | 2023-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11702418-B2 | SOS1 inhibitors | SOS1, SOS2, SOST | ALDH1A1 3367/4885KDM4E 2892/4885HPGD 3484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.