Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | CA4 | P22748 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA3 | P07451 | 1/20 | 0.48 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | SNCA | P37840 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.48 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10875625 | 0.98 | KDM4E (0.49) | CA1CA2CA4NFKB1KDM4E | |
| SCHEMBL2535572 | 0.98 | KDM4E (0.49) | CA1CA2CA4NFKB1KDM4E | |
| SCHEMBL187151 | 0.85 | KDM4E (0.51) | CA1CA2CA4NFKB1KDM4E | |
| SCHEMBL187153 | 0.85 | KDM4E (0.51) | CA1CA2CA4NFKB1KDM4E | |
| SCHEMBL28518886 | 0.84 | MAPT (0.56) | CA1CA2KDM4ECA12CA7 | |
| SCHEMBL21317660 | 0.84 | KDM4E (0.50) | CA1CA2CA4NFKB1KDM4E | |
| SCHEMBL6655468 | 0.84 | KDM4E (0.50) | CA1CA2CA4NFKB1KDM4E | |
| SCHEMBL5320426 | 0.82 | CA1 (0.50) | CA1CA2CA4NFKB1KDM4E | |
| SCHEMBL16048951 | 0.81 | CA1 (0.55) | CA1CA2CA4NFKB1KDM4E | |
| SCHEMBL16048950 | 0.81 | CA1 (0.55) | CA1CA2CA4NFKB1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109310660-A | Therapeutic combination and application thereof | 蜜纽康新西兰有限公司 | 2019-02-05 | — | — | CN | disclosed |