Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.97 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.97 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.97 |
| ▸ | CA12 | O43570 | 3/20 | 0.53 |
| ▸ | CA1 | P00915 | 3/20 | 0.53 |
| ▸ | CA2 | P00918 | 3/20 | 0.53 |
| ▸ | CA9 | Q16790 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Temozolomide SCHEMBL3270220 | 0.98 | MEN1 (1.00) | MEN1PABPC1KMT2ACA12CA1 | |
| Temozolomide SCHEMBL3739 | 0.98 | MEN1 (1.00) | MEN1PABPC1KMT2ACA12CA1 | |
| Temozolomide SCHEMBL4746638 | 0.97 | MEN1 (0.97) | MEN1PABPC1KMT2ACA12CA1 | |
| Temozolomide SCHEMBL3784250 | 0.97 | MEN1 (0.97) | MEN1PABPC1KMT2ACA12CA1 | |
| Temozolomide SCHEMBL1534013 | 0.97 | MEN1 (0.97) | MEN1PABPC1KMT2ACA12CA1 | |
| Temozolomide SCHEMBL27721442 | 0.93 | MEN1 (0.89) | MEN1PABPC1KMT2ACA12CA1 | |
| Temozolomide SCHEMBL16227379 | 0.89 | MEN1 (0.82) | MEN1PABPC1KMT2ACA12CA1 | |
| Temozolomide SCHEMBL10168201 | 0.88 | MEN1 (0.81) | MEN1PABPC1KMT2ACA12CA1 | |
| Altretamine SCHEMBL27875070 | 0.88 | KMT2A (0.80) | MEN1PABPC1KMT2ACA12CA1 | |
| Temozolomide SCHEMBL4444959 | 0.87 | MEN1 (0.78) | MEN1PABPC1KMT2ACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110366561-A | The conditionity agonist of immune response | F星贝塔有限公司 | 2019-10-22 | — | — | CN | disclosed |
| CN-109563171-A | In conjunction with the binding molecule of PD-L1 and LAG-3 | F星德尔塔有限公司 | 2019-04-02 | — | — | CN | disclosed |
| CN-109311993-A | LAG-3 binding member | F星贝塔有限公司 | 2019-02-05 | — | — | CN | disclosed |