SCHEMBL28275604

SCHEMBL28275604

[c]1ccccc1-c1cccc2occc12

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39
FTO Q9C0B1 1/20 0.39
KCNA3 P22001 1/20 0.36
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33
CYP1A1 P04798 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP1B1 Q16678 1/20 0.31
FADS1 O60427 1/20 0.31
EED O75530 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10325067 0.79 MAOB (0.40) MAOAMAOBFTO
SCHEMBL2591756 0.72 HPGD (0.38) MAOACYP1A2
SCHEMBL28869362 0.72 SLC6A2 (0.32) SLC6A2SLC6A4SLC6A3CYP1A2
SCHEMBL2761711 0.72 MEN1 (0.32) MAOA
SCHEMBL147800 0.72 POLB (0.40) CYP1A2
SCHEMBL2143620 0.72 MAOB (0.45) MAOAMAOBFTOKCNA3SLC6A2
SCHEMBL28275557 0.71 MAOA (0.37) MAOAMAOBFTOKCNA3SLC6A2
SCHEMBL10325492 0.71 ALOX5 (0.49) MAOA
SCHEMBL5486710 0.71 MAOA (0.32) MAOAMAOBFTOKCNA3
SCHEMBL22115937 0.71 MAOA (0.48) MAOAMAOBFTOKCNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109311844-A Triaizine compounds, its manufacturing method and the organic electroluminescent device as constituent 东曹株式会社 2019-02-05 CN disclosed