SCHEMBL28275657

SCHEMBL28275657

O=C(CS)OC(=O)OC(=O)CS.[NaH].[NaH]

nearest known ligand 0.48

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.48
HSD17B10 Q99714 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11228176 0.97 TSHR (0.50) TSHRHSD17B10
SCHEMBL28177214 0.87 TSHR (0.53) TSHRHSD17B10
SCHEMBL407915 0.83
SCHEMBL27791611 0.80 TSHR (0.53) TSHRHSD17B10
SCHEMBL28277058 0.77 ALDH1A1 (0.38) TSHRHSD17B10
SCHEMBL11801096 0.75
SCHEMBL10630073 0.75 TSHR (0.48) TSHRHSD17B10
SCHEMBL2324008 0.73
SCHEMBL28277040 0.73 ALDH1A1 (0.39) TSHRHSD17B10
Ammonia Solution, Strong SCHEMBL28772739 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109265705-A Collagen thiolated derivative and its preparation method and application 中国科学院苏州纳米技术与纳米仿生研究所 2019-01-25 CN disclosed