Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | FDPS | P14324 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Imidazoleacetic Acid SCHEMBL360337 | 0.96 | — | — | |
| Imidazoleacetic Acid SCHEMBL2172193 | 0.94 | TBXAS1 (0.59) | TBXAS1GAASMN1; SMN2TAAR1HTT | |
| Imidazoleacetic Acid SCHEMBL17375738 | 0.94 | TBXAS1 (0.56) | TBXAS1GAASMN1; SMN2TAAR1HTT | |
| Imidazoleacetic Acid SCHEMBL15007471 | 0.94 | TBXAS1 (0.56) | TBXAS1GAASMN1; SMN2TAAR1HTT | |
| Imidazoleacetic Acid SCHEMBL28462628 | 0.89 | TBXAS1 (0.51) | TBXAS1GAASMN1; SMN2TAAR1HTT | |
| Imidazoleacetic Acid SCHEMBL26627272 | 0.89 | TBXAS1 (0.51) | TBXAS1GAASMN1; SMN2TAAR1HTT | |
| SCHEMBL11840829 | 0.86 | — | — | |
| Imidazoleacetic Acid SCHEMBL8706716 | 0.84 | TBXAS1 (0.47) | TBXAS1GAASMN1; SMN2TAAR1HTT | |
| Imidazoleacetic Acid SCHEMBL16339368 | 0.83 | TBXAS1 (0.46) | TBXAS1GAASMN1; SMN2TAAR1HTT | |
| SCHEMBL8519473 | 0.81 | TBXAS1 (0.50) | TBXAS1GAASMN1; SMN2TAAR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020179-B9 | PEPTIDE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, METHOD FOR PRODUCING THE SAME, USE OF SAID DERIVATIVES AND PHARMACEUTICAL COMPOSITION | OTKRYTOE AKTSIONERNOE OBSCHESTVO OTECHESTVENNYE LEKARSTVA (RU) | 2011-02-02 | — | — | EP | disclosed |
| EP-2229935-A1 | Peptide derivatives or pharmaceutically acceptable salts thereof, method for producing the same, use of said derivatives and pharmaceutical composition | Nebolsin, Vladimir Evgenievich (RU) | 2010-09-22 | — | — | EP | disclosed |
| EP-1020179-B1 | PEPTIDE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, METHOD FOR PRODUCING THE SAME, USE OF SAID DERIVATIVES AND PHARMACEUTICAL COMPOSITION | OTKRYTOE AKTSIONERNOE OBSCHEST (RU) | 2009-12-09 | — | — | EP | disclosed |
| EP-1020179-A2 | PEPTIDE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, METHOD FOR PRODUCING THE SAME, USE OF SAID DERIVATIVES AND PHARMACEUTICAL COMPOSITION | Nebolsin, Vladimir Evgenievich (RU) | 2000-07-19 | — | — | EP | disclosed |