Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25111585 | 0.71 | DPP4 (0.48) | SMN1; SMN2TSHRDPP4KDM4ELMNA | |
| SCHEMBL597171 | 0.71 | NAMPT (0.46) | SMN1; SMN2TSHRMAPTPOLB | |
| SCHEMBL597029 | 0.71 | NAMPT (0.46) | SMN1; SMN2TSHRMAPTPOLB | |
| SCHEMBL3633044 | 0.71 | MAPT (0.39) | SMN1; SMN2TSHRMAPTALDH1A1HTT | |
| SCHEMBL597028 | 0.71 | NAMPT (0.46) | SMN1; SMN2TSHRMAPTPOLB | |
| SCHEMBL935614 | 0.70 | CAD (0.43) | TSHRLMNARAB9AHTT | |
| SCHEMBL935613 | 0.70 | CAD (0.43) | TSHRLMNARAB9AHTT | |
| SCHEMBL28926783 | 0.70 | CAD (0.43) | TSHRLMNARAB9AHTT | |
| SCHEMBL13445004 | 0.69 | CHRNB2 (0.50) | SMN1; SMN2TSHRKDM4ELMNARAB9A | |
| SCHEMBL30701613 | 0.68 | DPP4 (0.42) | SMN1; SMN2TSHRDPP4ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109384701-A | It is a kind of to be used to prepare compound and the preparation method and application thereof of the Sha Ku than song | 上海朴颐化学科技有限公司 | 2019-02-26 | — | — | CN | disclosed |