SCHEMBL2827686

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2828428	0.84	HDAC3 (0.52)	SLC16A3FYNMALT1HDAC6KCNJ6
	SCHEMBL3631457	0.82	SMN1; SMN2 (0.56)	SLC16A3FYNSMN1; SMN2CYP1A2CYP2C9
	SCHEMBL2825591	0.80	GRN (0.56)	SLC16A3HDAC6SMN1; SMN2CYP1A2CYP2C9
	SCHEMBL27992973	0.79	SLC16A3 (0.47)	SLC16A3MALT1HDAC6NR1H2MARS1
	SCHEMBL2225688	0.78	SLC16A3 (0.59)	SLC16A3MALT1HDAC6MARS1SMN1; SMN2
	SCHEMBL2824124	0.74	FFAR1 (0.60)	—
	SCHEMBL2825520	0.73	SMN1; SMN2 (0.54)	HDAC6SMN1; SMN2CYP1A2CYP2C9MEN1
	SCHEMBL19869344	0.72	GRN (0.46)	SLC16A3KCNJ6KCNJ5KCNJ3SMN1; SMN2
	SCHEMBL19531685	0.71	KDM4E (0.47)	KCNJ6KCNJ5KCNJ3SMN1; SMN2MEN1
	SCHEMBL28835323	0.71	KCNJ6 (0.49)	KCNJ6KCNJ5KCNJ3SMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.