Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.67 |
| ▸ | RAB9A | P51151 | 5/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | PDE9A | O76083 | 4/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | TNKS | O95271 | 1/20 | 0.57 |
| ▸ | GUSB | P08236 | 1/20 | 0.57 |
| ▸ | PARP1 | P09874 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28277006 | 0.86 | KDM4E (0.63) | KDM4ERAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL28277008 | 0.83 | TYMS (0.63) | KDM4ERAB9ASMN1; SMN2ALDH1A1PDE9A | |
| SCHEMBL28805360 | 0.82 | RAB9A (0.72) | KDM4ERAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL28278329 | 0.81 | KDM4E (1.00) | KDM4ERAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL15679346 | 0.75 | KDM4E (0.63) | KDM4ERAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL16981655 | 0.75 | PDE9A (1.00) | PDE9A | |
| SCHEMBL3121699 | 0.74 | APP (0.73) | SMN1; SMN2MAPTLMNAALDH1A1TP53 | |
| SCHEMBL29593104 | 0.73 | TNKS (1.00) | KDM4ERAB9ANPC1MAPTTNKS | |
| SCHEMBL8502164 | 0.73 | TNKS (1.00) | KDM4ERAB9ANPC1MAPTTNKS | |
| SCHEMBL9776727 | 0.73 | KDM4E (0.68) | KDM4ERAB9ASMN1; SMN2NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109422697-A | The method for synthesizing Quinazol derivative | 南京理工大学 | 2019-03-05 | — | — | CN | disclosed |